We report on a young patient with cancer of unknown primary origin with occlusion of the superior vena cava due to mediastinal lymphadenopathy. In order to continue infusion of palliative chemotherapy a central venous port system was radiologically implanted via a right femoral vein access. The port reservoir was placed craniomedial to the right anterior superior iliac spine. This approach was considered convenient in respect to comfort in wearing trousers. In addition, at this site the port reservoir is easily accessible for medical staff. It was possible to draw blood via the port system and to infuse the chemotherapy without complications. The present case shows that in cases of occlusion of the superior vena cava radiological implantation of a central venous port system via a femoral vein access is a useful option.

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