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Acquired Hepatocerebral Degeneration and Accumulation of Manganese.
Ann Indian Acad Neurol
January 2025
Department of Neurology, Princess Esra Hospital, Deccan College of Medical Sciences, Hyderabad, Telangana, India.
A Rare Cause of Acquired Non-Wilsonian Hepato-Cerebral Degeneration in a Middle-Aged Woman.
Cureus
October 2024
Department of Acute Medicine, University Hospitals Plymouth NHS Trust, Plymouth, GBR.
Manganese is an essential trace mineral that has a vital role in maintaining various body functions. Manganese toxicity, referred to as Manganism, causing parkinsonism is a well-known phenomenon that occurs secondary to chronic environmental and occupational exposure to manganese. Patients with underlying chronic liver disease are also susceptible to the toxic accumulation of manganese since it essentially undergoes biliary excretion.
View Article and Find Full Text PDFSecondary parkinsonism associated with focal brain lesions.
Front Neurol
September 2024
Department of Neurology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Article Synopsis
- Focal imaging abnormalities in parkinsonism patients indicate a secondary cause, necessitating a unique diagnostic and treatment approach.
- Various factors such as vascular issues, brain injuries, and toxic exposures can lead to secondary parkinsonism, presenting with symptoms like rigidity and bradykinesia, often without rest tremor.
- Neuroimaging, especially MRI, is vital for diagnosis, as recognizing imaging abnormalities in context can lead to effective treatment; many secondary forms are reversible, improving our understanding of Parkinson's disease and brain function.
Acquired chronic hepatocerebral degeneration (CAHD) - Simulation of parkinsonism, secondary to chronic liver disease.
Rev Esp Enferm Dig
August 2024
Aparato Digestivo, Hospital Universitario Torrecárdenas, España.
Acquired chronic hepatocerebral degeneration (CAHD) is a rare and irreversible neurological disorder that can occur in patients with chronic liver disease. It is characterized by neurological symptoms similar to parkinsonism and the presence of brain damage secondary to manganese deposition. We present the case of a 60-year-old patient with episodes of recurrent hepatic encephalopathy and diagnosis of CAHD.
View Article and Find Full Text PDFReversibility of Acquired Hepatocerebral Degeneration After Living Donor Liver Transplantation: A Single-Center Experience.
J Clin Exp Hepatol
June 2024
Department of Liver Transplant, Shifa International Hospital, Islamabad, Pakistan.
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