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Associations Between Lead and Cadmium Exposure and Subclinical Cardiovascular Disease in U.S. Adults.

Cardiovasc Toxicol

January 2025

Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.

The impact of lead and cadmium exposure on subclinical cardiovascular disease (CVD), indicated by elevated high-sensitivity cardiac troponin (hs-cTnT) and N-terminal pro b-type natriuretic peptide (NT-proBNP) remains uncertain. We analyzed data from participants aged 20 and older, without overt CVD, in the National Health and Nutrition Examination Survey (NHANES; 1999-2004). Elevated lead and cadmium levels were defined as 3.

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Wealth resources has received little attention when studying how socioeconomic status shapes health outcomes. In the United States (USA), there is a growing body of evidence acknowledging a widening racial/ethnic wealth gap. However, little is known about wealth's role in shaping health inequity.

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Racial Disparities in Time to Huntington Disease Diagnosis in North America: An ENROLL-HD Analysis.

Neurol Clin Pract

October 2024

Department of Neurology (AM, YB, SLP), David Geffen School of Medicine; Institute for Society and Genetics (AM); Interdepartmental Undergraduate Neuroscience Program (AM), UCLA; Division of General Internal Medicine (ACO), Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO; Department of Neurology (YB), Cedars Sinai Health Center, Los Angeles, CA; and Division of General Internal Medicine and Health Services Research (AB), Department of Medicine, David Geffen School of Medicine, UCLA.

Background And Objectives: There are well-documented racial and ethnic disparities in access to neurologic care and disease-specific outcomes. Although contemporary clinical and neurogenetic understanding of Huntington disease (HD) is thanks to a decades-long study of a Venezuelan cohort, there are a limited number of studies that have evaluated racial and ethnic disparities in HD. The goal of this study was to evaluate disparities in time from symptom onset to time of diagnosis of HD.

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Importance: Incidence of distant stage prostate cancer is increasing in the United States. Research is needed to understand trends by social and geographic factors.

Objective: To examine trends in prostate cancer incidence and mortality rates in California by stage, age, race and ethnicity, and region.

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Neurodegeneration is presumed to be the pathological process measure most proximal to clinical symptom onset in Alzheimer Disease (AD). Structural MRI is routinely collected in research and clinical trial settings. Several quantitative MRI-based measures of atrophy have been proposed, but their low correspondence with each other has been previously documented.

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