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Diagnosis and treatment of autonomic failure, pain and sleep disturbances in Parkinson's disease: guideline "Parkinson's disease" of the German Society of Neurology.
J Neurol
January 2025
Department of Neurology, LMU University Hospital, Ludwig-Maximilians-Universität (LMU) München, Munich, Germany.
Background And Objective: Non-motor symptoms frequently develop throughout the disease course of Parkinson's disease (PD), and pose affected individuals at risk of complications, more rapid disease progression and poorer quality of life. Addressing such symptom burden, the 2023 revised "Parkinson's disease" guideline of the German Society of Neurology aimed at providing evidence-based recommendations for managing PD non-motor symptoms, including autonomic failure, pain and sleep disturbances.
Methods: Key PICO (Patient, Intervention, Comparison, Outcome) questions were formulated by the steering committee and refined by the assigned authors.
Clinical Manifestations.
Alzheimers Dement
December 2024
Azienda Ospedaliero Universitaria Pisana, Pisa, PI, Italy.
Background: Despite being off-label, antipsychotics and antidepressants are widely prescribed to manage Behavioural and Psychological Symptoms of Dementia (BPSD). Aim of our study was to assess the evolution of BPSD and psychoactive pharmacological therapy in older patients with dementia.
Method: In this retrospective observational study, outpatients with dementia underwent a Comprehensive Geriatric Assessment (ADL, IADL, CFS and CIRS), at baseline, 6-month and 12-month follow-up visits.
Omega-3 fatty acids and sleep: recent advances in understanding effects and mechanisms.
Curr Opin Clin Nutr Metab Care
December 2024
Brain, Performance and Nutrition Research Centre, Faculty of Health and Life Sciences, Northumbria University, UK.
Purpose Of Review: Sleep disturbance and low dietary intake of omega-3 fatty acids are common in modern society. Previous research shows that omega-3 fatty acids play an integral role in the regulation of sleep processes, but efficacy data in adults have been equivocal to date. This review examines recent studies highlighting the effects of omega-3 fatty acids on sleep quality and circadian processes.
View Article and Find Full Text PDFCare trajectories and adherence to respiratory management recommendations in persons living with amyotrophic lateral sclerosis: a ten-year cohort study in a French tertiary university centre.
Amyotroph Lateral Scler Frontotemporal Degener
January 2025
University Grenoble Alpes, Grenoble, France.
: This study determined real-life care trajectories before and after initiation of noninvasive ventilation (NIV) in patients with amyotrophic lateral sclerosis (ALS). Caregiver adherence to respiratory management recommendations and the associated survival rate of people with ALS were also assessed. : Data were obtained from a tertiary center prospective ALS database that included 10 years of follow-up data for people with ALS.
View Article and Find Full Text PDFThe Pittsburgh Sleep Quality Index (PSQI) Applied to Cancer Patients: Psychometric Properties and Factors Affecting Sleep Quality.
Cancer Invest
January 2025
Department of Neurology and Experimental Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Objective: Cancer patients frequently report sleep problems. The Pittsburgh Sleep Quality Index (PSQI) is a 19-item instrument for assessing sleep problems. The main objective of this study was to analyze the usefulness of the PSQI in oncological research.
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