Effects of chromium-loaded chitosan nanoparticles (Cr-CNP) on growth performance, blood metabolites, immune traits, and tissue chromium in finishing pigs were investigated. A total of 160 crossbred barrows (66.06 ± 1.01 kg initial weight) were randomly divided into four groups, each group with four pens, ten pigs per pen. Pigs were fed on the same basal diet supplemented with 0 (the control), 100, 200, and 400 μg/kg Cr from Cr-CNP. All pigs were given free access to feed and water. Eight pigs from each treatment were selected to collect blood and tissue samples after 35 days on trial for analysis of blood metabolites and immune traits and tissue chromium. The results of feeding trial showed that there were no significant difference in growth performance between control and Cr-CNP-treated groups. The supplementation of Cr-CNP decreased serum glucose (P < 0.001) in a linear and quadratic manner. Serum immunoglobulins A and M were linearly increased in Cr-CNP-treated groups (P < 0.001), and serum complement 4 in Cr-CNP-treated groups was also linearly increased (P < 0.05). Cr-CNP supplementation linearly increased the chromium content in the blood, longissimus muscle, heart, liver, kidney, and pancreas (P < 0.001). These results suggested that dietary supplementation of Cr as Cr-CNP affects serum glucose, influences immune status, and increases the tissue chromium content of blood, muscle, and selected organs in finishing pigs.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s12011-012-9428-3 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Particulate Hexavalent Chromium Exposure Induces DNA Double-Strand Breaks and Inhibits Homologous Recombination Repair in Rat and Human Lung Tissues.
Chemosphere
December 2024
Wise Laboratory of Environmental and Genetic Toxicology; Department of Pharmacology and Toxicology. Electronic address:
Lung cancer is an important human health concern because of its high mortality rate, with many cases caused by environmental chemicals other than tobacco. Particulate hexavalent chromium [Cr(VI)] is a well-established human lung carcinogen, but how Cr(VI) induces lung cancer is poorly understood. Chromosome instability, a hallmark of lung cancer, is considered a major driving factor in Cr(VI)-induced lung cancer.
View Article and Find Full Text PDFEnvironmental risks and agronomic benefits of industrial sewage sludge-derived biochar.
PeerJ
December 2024
Department of Chemistry, University of Trnava, Trnava, Slovakia.
Article Synopsis
- - The study evaluates the safety of using thermochemically treated sewage sludge from a distillery's wastewater treatment plant as a soil additive by examining its physicochemical properties and the bioaccumulation of heavy metals in maize.
- - Pyrolysis at 400 °C alters the sludge's characteristics positively, increasing pH, carbon, nitrogen, and ash content, while reducing electrical conductivity, cation exchange capacity, and harmful polycyclic aromatic hydrocarbons.
- - Results show that adding 1% biochar from the treated sludge improves soil properties and doesn't enhance heavy metal uptake in maize or affect cress seed germination, though it does impact the soil's microbial community.
Decoding Chemotherapy Resistance of Undifferentiated Pleomorphic Sarcoma at the Single Cell Resolution: A Case Report.
J Clin Med
November 2024
Research Institute of Molecular and Cellular Medicine, Peoples' Friendship University of Russia (RUDN University), 115093 Moscow, Russia.
Undifferentiated pleomorphic sarcoma (UPS) is a highly malignant mesenchymal tumor that ranks as one of the most common types of soft tissue sarcoma. Even though chemotherapy increases the 5-year survival rate in UPS, high tumor heterogeneity frequently leads to chemotherapy resistance and consequently to recurrences. In this study, we characterized the cell composition and the transcriptional profile of UPS with resistance to chemotherapy at the single cell resolution.
View Article and Find Full Text PDFComputational wear prediction of articular cartilage based on a new anisotropic wear law.
J Biomech
December 2024
Tribology Research Institute, School of Mechanical Engineering, Southwest Jiaotong University, Chengdu 610031, China. Electronic address:
Excessive wear can result in irreversible damage to the cartilage. Experimental studies indicate that cartilage wear is significantly influenced by both the orientation of unidirectionally aligned surface fibers and the biphasic structure of the tissue. Given challenges with invasive in vivo wear experiments, there is a pressing need for computational models to predict wear of the cartilage accurately.
View Article and Find Full Text PDFMicrobes mediated alleviation of chromium (Cr VI) stress for improved phytoextraction in fodder maize ( L.) cultivar.
Heliyon
December 2024
ICAR-Indian Institute of Maize Research, Ludhiana, 141004, Punjab, India.
This study investigates the potential of chromium (VI) resistant bacterial isolates to alleviate heavy metal stress in fodder maize plants and enhance phytoremediation. Twenty-one bacterial strains were isolated from contaminated water, with five strains; (BHR1) (BHR2), (BHR4), (BHR5) and (BHR6) selected based on their significant plant-growth promoting (PGP) traits and heavy metal tolerance. Under chromium (Cr VI) stress, the BHR1 strain significantly improved seed germination, seedling length and vigor index of fodder maize variety (J 1007) especially at 150 mg/L Cr (VI), where these parameters increased by 3.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!