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| http://dx.doi.org/10.1128/AAC.00478-12 | DOI Listing |
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A systematic review and meta-analysis: rising prevalence of colistin resistance in ICU-acquired Gram-negative bacteria.
APMIS
January 2025
Laboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Colistin is a last-resort treatment for multidrug-resistant Gram-negative bacterial infections, particularly in critically ill patients. Nevertheless, it remains a major threat to public health. We assessed the proportion of colistin-resistant Gram-negative isolates from intensive care unit (ICU) infections in different years, areas, pathogens, and antimicrobial susceptibility tests (AST).
View Article and Find Full Text PDFQuantification of Antimicrobial Use on Commercial Broiler Farms in Pakistan.
Animals (Basel)
December 2024
Veterinary Epidemiology Unit, Department of Internal Medicine, Reproduction and Population Medicine, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium.
Pakistan has a large, intensive broiler production industry, where antimicrobials are extensively used for both therapeutic and prophylactic purposes. Monitoring antimicrobial use (AMU) at the farm level is crucial to guide interventions for antimicrobial stewardship. The objective of this study was to comprehensively quantify AMU on commercial broiler farms in Pakistan using different metrics.
View Article and Find Full Text PDFGreen synthesis of silver nanoparticles using Acroptilon repens aqueous extract and their antibacterial efficacy against multidrug-resistant Acinetobacter baumannii.
Mol Biol Rep
December 2024
Department of Biology, Varamin- Pishva Branch, Islamic Azad University, Varamin, 33817-74895, Iran.
Background: Acinetobacter baumannii is a critical pathogen associated with hospital-acquired infections, particularly in burn and intensive care unit (ICU) patients, and is notorious for its high level of antibiotic resistance. This study aims to evaluate the antibacterial potential of silver nanoparticles (AgNPs) synthesized using Acroptilon repens extract as a promising alternative treatment for combating multidrug-resistant A. baumannii.
View Article and Find Full Text PDFEpidemiological and Clinical Insights into : A Six-Year Study on Age, Antibiotics, and Specimens.
Int J Gen Med
December 2024
Department of Clinical Microbiology and Immunology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Background: This six-year retrospective study provides an in-depth analysis of the epidemiological and clinical patterns associated with () infections, focusing on age distribution, antibiotic resistance profiles, and specimen types.
Aim: The research examines the incidence and characteristics of non-Multi-Drug Resistant (non-MDR) and Multi-Drug Resistant (MDR) strains by reviewing patient records from January 2016 to December 2022.
Methods: Through a statistical analysis, the study highlights the incidence rates across diverse age groups and explores the impact of antibiotic treatment regimens on infection outcomes.
Molecular Identification of OXA Carbapenemase-Encoding Genes in Isolated from Patients in Critical Care in Egypt.
Surg Infect (Larchmt)
November 2024
Medical Microbiology and Immunology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
The emergence of carbapenem-resistant (CRAB) in hospitals, particularly within critical care units, has garnered substantial global concern. CRAB commonly arises from the degradation by various ß-lactamases. : We aimed to assess OXA-type carbapenemases in clinical isolates of obtained from an Egyptian tertiary care facility.
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