AI Article Synopsis
- The study investigates how minor salivary glands may be related to the occurrence of peritonsillar abscess (PTA) in patients.
- It includes 41 patients with PTA and measures amylase levels in their pus and serum, revealing significantly higher levels in the PTA group compared to those with neck abscesses.
- The findings suggest that high amylase levels might indicate minor salivary gland involvement, while lower levels could be linked to higher recurrence rates, pointing to the potential interplay between these glands and tonsillar infections in PTA development.
Article Abstract
Objectives: To study the relationship between peritonsillar abscess (PTA) and minor salivary glands surrounding the palatine tonsils.
Study Design: Prospective population-based study.
Settings: Tertiary care university hospital.
Subjects And Method: Prospective study including 41 patients with PTA and 6 patients with a neck abscess. Amylase levels of the pus and serum were measured and compared between the 2 groups. Clinical data regarding hospitalization length and recurrence rate were also collected.
Results: Of the 41 patients with PTA, 7 suffered from recurrent PTA. Average level of amylase in the pus of the PTA group was 3841 U/L versus 7.7 U/L in the neck abscess group (P < .001; median, 62 vs 9.5). Serum amylase was higher in the PTA group (49.3 U/L vs 37.3 U/L; P = .008). There were no recurrences in PTA patients with amylase greater than 65 U/dL in the pus in 0 of 20 (0%) versus 7 of 21 (33%) for amylase lower than 65 U/L (P = .01).
Conclusion: High amylase in the pus lends further support for involvement of minor salivary glands. However, high recurrence rates related to low amylase in the pus imply an additional pathogenesis possibly related to tonsillar infection. It is possible that both minor salivary glands as well as tonsillar infection play a role in the pathogenesis of peritonsillar infections.
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| http://dx.doi.org/10.1177/0194599812445552 | DOI Listing |
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