Object: Programmable valves (PVs) for shunting CSF have increasingly replaced nonprogrammable valves (NPVs). There have been only a few longer-term studies (≥ 5 years) conducted that have compared the effectiveness of NPVs with that of PVs for children with hydrocephalus, and only 1 study has reported NPVs as being favorable over PVs. The objective of this retrospective study was to compare the long-term survival of these 2 types of shunt valves.
Methods: The authors collected data for all patients who underwent CSF shunt insertion or revision between January 1, 2000, and December 31, 2008. Patients underwent follow-up for a minimum of 2 years postoperatively. Statistical analyses were done using chi-square, Kaplan-Meier survival curve, and multivariate analyses.
Results: A total of 616 valves were implanted, of which 313 were PVs and 303 were NPVs. Of these, 253 were original shunt implantations and 363 were revisions. The proportion of 5-year survival for NPVs (45.8%) was significantly higher than that for PVs (19.8%) (p = 0.0005, log-rank). The NPVs that survived longer than 6 months also survived through the 5th year better than the PVs (p = 0.0001).
Conclusions: The authors' data suggest that NPVs survive longer than PVs in children, but there is a need for prospective, case-control studies to confirm these data.
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http://dx.doi.org/10.3171/2012.1.PEDS10482 | DOI Listing |
AJNR Am J Neuroradiol
January 2025
From the Division of Neuroradiology, Department of Radiology (M.T.W., A.M., C.A.P.F.A., O.S, E.S.S.), and Department of Obstetrics and Gynecology (N.K.), Children's Hospital of Philadelphia, Philadelphia, PA, USA; Perelman School of Medicine (M.T.W., N.K., E.S.S.), Philadelphia, PA, USA; Division of Neuroradiology, Department of Radiology (C.A.P.F.A), Boston Children's Hospital, Boston, MA, USA; and Harvard Medical School (C.A.P.F.A), Boston, MA, USA.
Background And Purpose: Frontal paraventricular cystic changes have a varied etiology that includes connatal cysts, subependymal pseudocysts, necrosis, and enlarged perivascular spaces. These may be difficult to distinguish by neuroimaging and have a variety of associated prognoses. We aim to refine the neuroimaging definition of frontal horn cysts and correlate it with adverse clinical conditions.
View Article and Find Full Text PDFTrials
December 2024
Medical Research Council Unit, The Gambia at London School of Hygiene & Tropical Medicine, Fajara, The Gambia.
Randomized controlled trials are considered the "gold standard" for evaluating the effectiveness of an intervention. However, large-scale, cluster-randomized trials are complex and costly to implement. The generation of accurate, reliable, and high-quality data is essential to ensure the validity and generalizability of findings.
View Article and Find Full Text PDFJ Vasc Interv Radiol
December 2024
Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Japan; Department of Diagnostic Imaging, Faculty of Medicine, Hokkaido University, Sapporo, Japan; Global Center for Biomedical Science and Engineering, Faculty of Medicine, Hokkaido University, Sapporo, Japan.
Purpose: To investigate the change in serum albumin levels and hepatic reserve scores before and after portal vein stent placement (PVS) for post-surgical portal vein stenosis.
Material And Methods: A retrospective cohort of patients undergoing PVS after abdominal surgery between 2007 and 2021 was analyzed. Patients' age, sex, and PVS technical success (defined by portal vein patency at final portography) were evaluated.
J Endocrinol Invest
December 2024
Department of Urology, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, 410008, Hunan, China.
Circ Arrhythm Electrophysiol
December 2024
Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, GA (A. Midya, A. Madabhushi).
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