The article presents data concerning the prevalence of acute diseases and conditions in the Russian Federation. The main requirements are exposed concerning the laboratory diagnostics of acute conditions. The results of analysis of regulating documents concerning this issue are presented. The list of optimal laboratory tests and organizational options to be implemented in laboratory testing of patients with acute diseases and conditions in medical institutions is developed. The role and importance of principles of evidence medicine in choosing an optimal list of laboratory analysis to diagnose the acute conditions is demonstrated.

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