We study experimentally the dynamical heterogeneities occurring at slow shear, in a model amorphous glassy material, i.e., a 3D granular packing. The deformation field is resolved spatially by using a diffusive wave spectroscopy technique. The heterogeneities show up as localized regions of strong deformations spanning a mesoscopic size of about 10 grains and called the "hot spots." The spatial clustering of hot spots is linked to the subsequent emergence of shear bands. Quantitatively, their appearance is associated with the macroscopic plastic deformation, and their rate of occurrence gives a physical meaning to the concept of "fluidity," recently used to describe the local and nonlocal rheology of soft glassy materials.
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http://dx.doi.org/10.1103/PhysRevLett.108.135502 | DOI Listing |
J Chem Phys
December 2024
Department of Physics and Astronomy, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada.
Complex-Langevin field-theoretic simulations (CL-FTSs) provide an approximation-free method of calculating fluctuation corrections to the self-consistent field theory (SCFT) of block copolymer melts. However, the complex fields are prone to the formation of hot spots, which causes the method to fail. This problem has been attributed to an invariance under complex translations, which allows the system to drift away from the real-valued saddle-point of SCFT.
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December 2024
School of Basic Medical Science, Tsinghua University, 30 Shuangqing Rd., Haidian District, Beijing, 100084, China.
Modeling and predicting mutations are critical for COVID-19 and similar pandemic preparedness. However, existing predictive models have yet to integrate the regularity and randomness of viral mutations with minimal data requirements. Here, we develop a non-demanding language model utilizing both regularity and randomness to predict candidate SARS-CoV-2 variants and mutations that might prevail.
View Article and Find Full Text PDFJ Pharm Biomed Anal
December 2024
GICAPC Research Group, Department of Analytical Chemistry, University of Valencia, Burjassot, Valencia 46100, Spain. Electronic address:
This review article brings together two of the current hot-spots in the field of analytical chemistry, and more specifically in the sample preparation stage: the use of dispersive microextraction techniques, and the analysis of saliva. Due to saliva collection is minimally invasive, it is increasingly being considered in bioanalysis. Moreover, bioanalysis is routine and agglutinates a high number of samples demanding for fast results, thus high-throughput assays are highly required.
View Article and Find Full Text PDFSmall Methods
December 2024
Frumkin Institute of Physical Chemistry and Electrochemistry Russian Academy of Sciences, Leninsky pr., 31, building 4, Moscow, 119071, Russia.
A novel phthalocyanine-based hybrid nanofilm is for the first time successfully applied as an oxidative platform for surface enhanced Raman spectroscopy (SERS) sensing to fine-resolve Raman-inactive compounds. The hybrid is formed by self-assembly of zinc(II) 2,3,9,10,16,17,23,24-Octa[(3',5'-dicarboxy)-phenoxy]phthalocyaninate (ZnPc*) with the solid-supported monolayer of graphene oxide (GO) mediated by zinc acetate metal cluster. Atomic force microscopy, UV-vis and fluorescence spectroscopies confirm that this simple coordination motive in combination with molecular structure of ZnPc* prevents contact quenching of the light-excited triplet state through aromatic stacking with GO particles.
View Article and Find Full Text PDFNanotechnology
December 2024
Chemistry and Biochemistry, North Carolina Central University, North Carolina Central University USA, Durham, 27707-3129, UNITED STATES.
Ciprofloxacin (CIP) is a widely used antibiotic, and its presence in water bodies poses a risk due to its resistance to conventional wastewater treatment processes. The accumulation of such pharmaceuticals can disrupt aquatic ecosystems, harm aquatic life, and contribute to ecological imbalances. Therefore, the degradation of CIP is of immense environmental significance.
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