AI Article Synopsis
- The study examined how obesity affects outcomes after pancreaticoduodenectomy (PD) in 97 patients, categorizing them based on body mass index (BMI).
- Despite the overall complication rate being similar for both normal and overweight groups, complications like pancreatic fistula and intra-abdominal fluid collection were notably more frequent in overweight patients.
- The research suggests that addressing modifiable risk factors for complications in overweight patients during the perioperative period is important, although mortality rates did not significantly differ between the two groups.
Article Abstract
Background/aims: The purpose of this study was to evaluate the impact of obesity on pancreaticoduodenectomy (PD) outcomes.
Methodology: Subjects were 97 patients undergoing PD at our institution between April 2005 and April 2011. All patients had data including body mass index (BMI). Patients were divided into two groups based on BMI; normal group (BMI <25kg/m2) and overweight group (BMI >25kg/m'). Perioperative outcomes were collected prospectively.
Results: There were no significant differences between the two groups in terms of intraoperative data, surgical time, blood loss and blood transfusion rates. The over-all complication rate was 50.0% (53.6% in the over- weight group and 47.1% in the normal group; p=0.55).The most common complication overall was pancreatic fistula (34.7%). There was also a significant difference in the rate of intra-abdominal fluid collection (four patients in the overweight group (14.3%) vs. two patients in the normal group (2.9%), respectively; p<0.05).There was no significant difference in the mortality rate between the normal group and the overweight group(3.6% vs. 0%, p=0.11).
Conclusions: Management of overweight patients in the perioperative period should therefore address any modifiable risk factors for operative complications.
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| http://dx.doi.org/10.5754/hge12169 | DOI Listing |
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