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Focal mandibular osteonecrosis following intraosseous anesthesia: A case report.

Int J Surg Case Rep

January 2025

Department of Oral and Maxillofacial Surgery, AZORG Hospital, Aalst, Belgium. Electronic address:

Introduction And Importance: Intraosseous anesthesia (IOA), an important technique in dental anesthesia, delivers anesthetic directly into the bone, enhancing patient comfort and minimizing side effects. Despite advantages, several disadvantages are known such as injection discomfort, root damage, mechanical obstructions and needle fractures. This report highlights a rare yet significant complication of focal mandibular osteonecrosis following IOA.

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The risk of cytokine release syndrome (CRS) in patients with infections prior to chimeric antigen receptor T-cell (CAR T-cell) therapy represents an important and underreported event. Patients with active infections needing prompt CAR T-cell therapy to treat aggressive hematologic malignancies remain a clinical challenge. This case describes the clinical course of a 35-year-old male patient with relapsed/refractory T-cell/histiocyte-rich large B-cell lymphoma who received axicabtagene ciloleucel.

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Article Synopsis
  • Prevotella species are typically harmless bacteria found in the intestines and mouth but can cause infections in immune-compromised individuals.
  • A 35-year-old man presented with high fever and chest pain, showing signs of an infection with severe respiratory symptoms and poor oral hygiene.
  • After medical imaging revealed a loculated pyopneumothorax, a chest tube was inserted, draining foul-smelling pus that tested positive for Prevotella Intermediata, which responded well to treatment.
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Article Synopsis
  • Aspergillomas are benign lung growths caused by the fungus Aspergillus fumigatus, primarily affecting immunocompromised patients, with most cases being asymptomatic and requiring specific diagnostic tests for confirmation.
  • A case study details a 35-year-old man experiencing symptoms like night sweats and a cough, resulting in a diagnosis of aspergillomas through imaging and microscopic examination.
  • Although aspergillomas are linked to chronic pulmonary aspergillosis and can be serious, surgery is often necessary due to high rates of mortality and morbidity associated with the condition.*
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Article Synopsis
  • * A specific case involved a 35-year-old patient on hemodialysis who developed symptoms like nausea and vomiting after using intranasal corticosteroids, leading to an esophagitis diagnosis confirmed by biopsy and PCR testing for HSV-1.
  • * Treatment with valacyclovir successfully relieved the symptoms, highlighting that while HE is rare in immunocompetent patients, certain medications like corticosteroids may increase the risk, and any concerning symptoms should prompt
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