We evaluated 16 patients, 2 weeks to 8 years of age (median: 18 months), operated on for ectopic ureterocele. Five patients, in whom the upper kidney, drained by the ureter with the ureterocele, was viable, were submitted to excision of the ureterocele with reimplantation of the double ureter (n = 4) or high ureteroureterostomy (n = 1). A 2-week-old baby with a non-functioning kidney was treated by nephroureterectomy. The remaining 10 children with a non-functioning upper part of a duplex kidney were submitted to heminephrectomy with subtotal ureterectomy. In this group of patients no problems arose from the retained ureteral stump or the decompressed ureterocele, and vesicoureteral reflux accompanying the ureterocele resolved postoperatively in 6 of 10 ureters.
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Adv Sci (Weinh)
December 2024
Department of Kidney Research Institute, Seoul National University Medical Research Center, Seoul, South Korea.
Podocyte injury and proteinuria in glomerular disease are critical indicators of acute kidney injury progression to chronic kidney disease. Renal mitochondrial dysfunction, mediated by intracellular calcium levels and oxidative stress, is a major contributor to podocyte complications. Despite various strategies targeting mitochondria to improve kidney function, effective treatments remain lacking.
View Article and Find Full Text PDFFront Pharmacol
November 2024
Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Introduction: Chronic kidney disease (CKD) is a substantial global health issue with high morbidity and mortality. Yishen Paidu Pills (YSPDP) are effective concentrated water pills composed of four herbs developed by Wuhan Union Hospital to treat CKD. However, the mechanism of YSPDP action is largely unknown.
View Article and Find Full Text PDFNephrol Dial Transplant
November 2024
William Harvey Research Institute, Queen Mary University of London, Charterhouse Square, London.
Am J Physiol Cell Physiol
October 2024
Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Reduced PALMD expression is strongly associated with the development of calcified aortic valve stenosis; however, the role of PALMD in vascular calcification remains unknown. Calcified arteries were collected from mice to detect PALMD expression. Heterozygous knockout () mice were established to explore the role of PALMD in subtotal nephrectomy-induced vascular calcification.
View Article and Find Full Text PDFBMC Urol
July 2024
Department of Oncology, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, Jiefang Road No.15, Xiangyang, 441000, Hubei, China.
Background: Eosinophilic solid and cystic renal cell carcinoma (ESC-RCC) is a novel subtype of renal cell carcinoma characterized by its relatively low incidence and indolent behavior. We report a rare case of ESC-RCC concurrent with clear cell renal cell carcinoma (ccRCC) in a single kidney.
Case Presentation: A 48-year-old male, was found to have a mixed echogenic mass in the left kidney during a physical examination.
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