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Randomized controlled trials (RCTs) evaluating anti-cancer agents often lack generalizability to real-world oncology patients. Although restrictive eligibility criteria contribute to this issue, the role of selection bias related to prognostic risk remains unclear. In this study, we developed TrialTranslator, a framework designed to systematically evaluate the generalizability of RCTs for oncology therapies.
View Article and Find Full Text PDFPurpose Of Review: This review aims to evaluate the impact of artificial intelligence (AI) on cancer health equity, specifically investigating whether AI is addressing or widening disparities in cancer outcomes.
Recent Findings: Recent studies demonstrate significant advancements in AI, such as deep learning for cancer diagnosis and predictive analytics for personalized treatment, showing potential for improved precision in care. However, concerns persist about the performance of AI tools across diverse populations due to biased training data.
Development of a Breastfeeding and Lactation Medicine Division Over a Seven-Year Period: An Homage to Dr Ruth A. Lawrence.
Breastfeed Med
January 2025
Divisions of Breastfeeding and Lactation Medicine and Allergy Immunology, Department of Pediatrics, University of Rochester, Rochester, New York, USA.
Breastfeeding and Lactation Medicine (BFLM) programs at academic medical centers are uncommon but expanding. Our academic medical center, with a long legacy of leadership in BFLM, established a BFLM program in 2016 and launched a dedicated division in 2022. To describe the strategy, services, measures, and challenges facing our multidisciplinary academic BFLM program in its first 8 years.
View Article and Find Full Text PDFThe Role of the Clinical Laboratory in Diagnostic Stewardship and Population Health.
J Appl Lab Med
January 2025
Project Santa Fe Foundation, Salt Lake City, UT, United States.
Background: As healthcare identifies new opportunities to provide patient services and moves from volume to value payment models, the clinical laboratory is in an ideal position to serve as a catalyst for these changes. In 2017, the Project Santa Fe Foundation (PSFF) was founded to support the clinical laboratory's role to promote the objectives of population health and value-based healthcare. The initiative, known as Clinical Lab 2.
View Article and Find Full Text PDFJU:MP leads: sparking physical activity leadership and supporting positive youth development in a deprived community.
Front Sports Act Living
December 2024
Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford Royal Infirmary, Bradford, United Kingdom.
Introduction: Physical activity interventions in deprived communities should acknowledge the social, political, and cultural context in which they are delivered. Targeted young leaders programs can harness positive youth development principles and address these concerns by engaging underrepresented young people and developing them as physical activity leaders who can support local delivery efforts. Community-based Youth Leadership development programs are under-researched, and little is known about how to develop young people from deprived communities as physical activity leaders.
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