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Osteoid osteoma appearing after bony fracture in a girl with osteogenesis imperfecta.
Skeletal Radiol
January 2025
Department of Radiology, National Center for Child Health and Development, 2-10-1 Okura, Setagaya, Tokyo, Japan.
Article Synopsis
- * A 3-year-old girl with OI experienced a complete tibial fracture and, after recovery, developed spontaneous pain at the fracture site where new imaging revealed OO.
- * The case highlights the rare coexistence of OO and OI, suggesting that the combination of OI's bone fragility and a prior fracture may have contributed to a refracture in the same area.
FN1 promotes chondrocyte differentiation and collagen production via TGF-β/PI3K/Akt pathway in mice with femoral fracture.
Gene
February 2021
Department of Orthopedics, The Second Hospital of Jilin University, Changchun 130041, PR China. Electronic address:
Fibronectin (FN) functions as a potent stimulator of osteogenic differentiation, and bone fracture healing. In FN family, FN1 acts as an interactive protein gene product to mediate chondrocyte adhesion. However, its effect on fracture healing remains elusive.
View Article and Find Full Text PDFAtypical femoral fracture associated with delayed union for which the cessation of alendronate and daily administration of teriparatide contributed to fracture healing: histopathological evidence of the enhancement in bone formation parameters.
Mod Rheumatol Case Rep
January 2020
Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
A female patient with systemic lupus erythematosus developed an atypical femoral fracture of the left femur after 5 years of glucocorticoid and alendronate therapy. We performed intramedullary nailing. However, 1 week later, we performed a revision surgery using a locking plate and an iliac bone graft because of displacement at the fracture site.
View Article and Find Full Text PDFChinese topical herbal medicine gives additive effect on pharmaceutical agent on fracture healing.
J Tradit Chin Med
December 2019
Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong China.
Objective: To investigate the efficacy on the combination of oral strontium ranelate (SrR) with a topical Chinese herbal paste on facilitation of fracture healing.
Methods: An open fracture was created at the mid-shaft of the right tibia of rat. A herbal paste called CDR containing Honghua (Flos Carthami), Chuanxuduan (Radix Dipsaci Asperoidis) and Dahuang (Radix Et Rhizoma Rhei Palmati) was prepared.
Osteoblastoma of the clavicle at the site of a previous fracture-first case report and review of the literature.
Skeletal Radiol
October 2019
Division of Musculoskeletal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, 55 Fruit Street Yawkey 6E, Boston, MA, 02114, USA.
Osteoblastoma is a rare, benign primary tumor of bone, accounting for < 1% of all bone tumors. We report the case of a 27-year-old female who developed pain and swelling five and a half years after a clavicular fracture and was subsequently found to have an osteoblastoma arising at the fracture site. This is the first reported case of an osteoblastoma developing after a fracture, although osteoid osteomas, which are histologically indistinguishable from osteoblastomas, have been reported at prior fracture sites.
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