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Safety and tolerability of a 6-week course of oseltamivir prophylaxis for seasonal influenza in children. | LitMetric

AI Article Synopsis

  • A study was conducted with 49 children aged 1-12 years who took oseltamivir for 6 weeks to prevent influenza.
  • Out of these, 17 children reported a total of 22 adverse events, with three likely linked to the medication (nausea or vomiting).
  • No serious adverse events occurred, and the medication's tolerability was similar to data from shorter treatment studies.

Article Abstract

In an open-label study, 49 children aged 1-12 years received oseltamivir (30-75 mg once daily depending on bodyweight) for 6 weeks for influenza prophylaxis. Seventeen participants reported 22 adverse events (AEs); in three participants, AEs were considered probably drug related (nausea or vomiting). No serious AEs were reported. The tolerability profile was similar to pooled safety data from treatment studies (duration of 5 days) in children.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780728PMC
http://dx.doi.org/10.1111/j.1750-2659.2012.00367.xDOI Listing

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