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Critical Issues in the Management of CRMS/CFSPID Children: A National Real-World Survey.
Pediatr Pulmonol
January 2025
IRCCS Istituto Giannina Gaslini, Cystic Fibrosis Center, Genoa, Italy.
Background: Notwithstanding guidance from the European Cystic Fibrosis (CF) Society (ECFS) neonatal screening (NBS) working group, significant variation persists in the evaluation and management of Cystic Fibrosis Screen Positive, Inconclusive Diagnosis (CFSPID) subjects, leaving many aspects of care under debate. This study reports the results of a national survey investigating management and treatment approaches of pre-school CFSPIDs in Italy.
Methods: In February 2024, a comprehensive questionnaire was distributed to all Italian CF centers.
Design and Test of a Calibration System for Avalanche Photodiodes Used in X-Ray Compton Polarimeters for Space.
Sensors (Basel)
December 2024
SCAI Connect s.r.l., Via Vincenzo Lamaro 51, 00173 Rome, Italy.
The development and calibration of a measurement system designed for assessing the performance of the avalanche photodiodes (APDs) used in the Compton scattering polarimeter of the CUSP project is discussed in this work. The designed system is able to characterize the APD gain GAPD and energy resolution across a wide range of temperatures (from -20 °C to +60 °C) and bias voltages Vbias (from 260 V to 410 V). The primary goal was to experimentally determine the GAPD dependence on the and Vbias in order to establish a strategy for stabilizing GAPD by compensating for fluctuations, acting on Vbias.
View Article and Find Full Text PDFSurface Behaviours of Humpback Whale at Nosy Be (Madagascar).
Biology (Basel)
November 2024
Department of Biology, Ecology and Earth Sciences, University of Calabria, 87036 Rende, Italy.
The surface behaviours of humpback whales were studied in the presence of a whale-watching vessel at Nosy Be (Madagascar) during whale-watching activities, in order to characterise the ethogram of these animals. Data were collected from July to October 2018. Of the 75 total trips, humpback whales were observed 68 times and different types of aggregations were observed: Groups (33.
View Article and Find Full Text PDFGlobal organelle profiling reveals subcellular localization and remodeling at proteome scale.
Cell
December 2024
Chan Zuckerberg Biohub, San Francisco, CA, USA. Electronic address:
Defining the subcellular distribution of all human proteins and their remodeling across cellular states remains a central goal in cell biology. Here, we present a high-resolution strategy to map subcellular organization using organelle immunocapture coupled to mass spectrometry. We apply this workflow to a cell-wide collection of membranous and membraneless compartments.
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