The concept of addiction has developed in France since the beginning of the 2000s. It has justified by common clinical aspects, high level of co-morbidities between addictions to psychoactive drugs, common cognitive and behavioral mechanisms, the impact of comparable psychological and genetic factors, the same neurobiological mechanisms and the same therapy options in many cases. Although some specificities remain in smoking management: absence of intoxication and abuse diagnosis in DSM-IV, less consensual politics of harm reduction, and own pharmacotherapy solutions. Despite what is commonly thought, tobacco is the most addictive amongst all psycho-active-substances in Western countries.
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Sci Rep
December 2024
Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
E-cigarette/vaping-associated lung injury (EVALI) is strongly associated with vitamin E acetate and often occurs with concomitant tetrahydrocannabinol (THC) use. To uncover pathways associated with EVALI, we examined cytokines, transcriptomic signatures, and lipidomic profiles in bronchoalveolar lavage fluid (BALF) from THC-EVALI patients. At a single center, we prospectively enrolled mechanically ventilated patients with EVALI from THC-containing products (N = 4) and patients with non-vaping acute lung injury and airway controls (N = 5).
View Article and Find Full Text PDFFront Plant Sci
December 2024
Key Laboratory in Flavor and Fragrance Basic Research, Zhengzhou Tobacco Research Institute, China National Tobacco Corporation, Zhengzhou, China.
Cigar tobacco leaves exhibited distinct regional characteristics, and aroma compounds were the key substances determining the different style features of cigars. However, the differences in aroma characteristics and the mechanisms of key aroma compound synthesis have not been fully elucidated. This study collected filler tobacco leaves (FTLs) from 5 representative domestic and international production regions.
View Article and Find Full Text PDFCureus
November 2024
Internal Medicine, Tata Main Hospital, Jamshedpur, IND.
Background: Vitamin B12 deficiency is a prevalent condition affecting a significant proportion of India's population, with implications for mental health. Despite its established link to psychiatric symptoms, vitamin B12 deficiency often remains underdiagnosed. The aim of this study is to highlight the association between vitamin B12 deficiency and acute psychosis, emphasizing the importance of early detection and treatment.
View Article and Find Full Text PDFAddict Sci Clin Pract
December 2024
Department of General Practice, School of Public Health and Preventive Medicine, Monash University, 553 St Kilda Rd, Level 5, Prahran, Melbourne, VIC, 3181, Australia.
Background: Family physicians (FPs) are the first point of contact for people who smoke who are seeking to quit smoking in Türkiye. We aimed to explore Turkish FPs knowledge, attitudes and perceptions of e-cigarettes as smoking cessation aids.
Methods: Eleven in-depth semi-structured interviews were conducted with FPs in Istanbul, Türkiye.
Harm Reduct J
December 2024
ABF Analytisch-Biologisches Forschungslabor GmbH, Semmelweisstr. 5, 82152, Planegg, Germany.
Background: Use of combustible cigarettes (CCs) and smokeless oral tobacco products are well documented risk factors for a variety of oral diseases. However, the potential oral health risks of using recently introduced (since about 2000) non-combustible tobacco/nicotine products (NCPs: electronic cigarettes (ECs), heated tobacco products (HTPs) and oral nicotine pouches (ONPs), remain poorly established.
Methods: This review evaluates published human studies on detrimental oral health effects in people who use NCPs compared to those smoking cigarettes and those not using any tobacco/nicotine product (NU).
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