AI Article Synopsis
- The review discusses the latest research on titanium implants that are functionalized with (bio)polymers for bone tissue engineering.
- It covers the necessary properties of materials and emphasizes titanium's bulk and surface characteristics, along with the importance of surface modifications.
- The article compares various organic modification methods and concludes with an overview of creating and assessing three-dimensional titanium scaffolds for bone applications.
Article Abstract
In the current review we aim to give an overview of the state of the art of the research on (bio)polymer functionalised titanium implants for bone tissue engineering applications. After a short introduction on bone tissue engineering and the requirements the applied materials have to meet, an extensive discussion on titanium in bone tissue engineering will be given. Starting with a short description of both the titanium bulk and surface properties, the requirement for surface modified titanium will be highlighted. The discussion will encompass inorganic and organic chemical modifications and a combination thereof with a focus on the organic modifications. Within the latter type of modification, physical adsorption, physical incorporation and covalent immobilisation will be compared. In the final part of the review an overview will be given of the fabrication and characterisation of three-dimensional titanium scaffolds.
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| http://dx.doi.org/10.2174/138161212800492903 | DOI Listing |
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