Objective: To determine the pattern of stability changes as a reflection of early healing around single-stage roughened-surface implants in humans utilizing resonance frequency analysis (RFA).
Materials And Methods: Hundred twenty-five patients who demanded dental implants were treated with two different implant (Nobel Biocare Replace™ and Strumman™ ITI) systems. Bone type was classified into four groups. RFA was used for direct measurement of implant stability on the day of implant placement and consecutively at 14, 30 and 60 days after placement. The data were analyzed with Student t test and regression analysis.
Results: Three-hundred four roughened surface implants placed in the maxilla and mandible were evaluated. In Replace™ implants the lowest mean stability measurement was at 30 days for all bone types and the stability did not change significantly in any of the bone types (p>0.05). ITI™ implants demonstrated the lowest stability at 60 days for type 1 and 30 days and baseline for type 2, 3 and 4 bones. In addition, there was significant differences in implant stability between bone types 1 and 4 (P<0.001), 2 and 3 (p<0.05), and bone types 3 and 4 (P=0.07) at all aforementioned times in ITI™ implants. In Replace™ implants, regarding the implant diameter, contrary to ITI implants, no significant stability changes were detected (p>0.05). No significant difference was observed regarding gender, age and lengths in both systems.
Conclusion: In comparison to ITI™ implants, Replace™ implants revealed no significant difference in the pattern of stability changes among different bone types.
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PLoS One
January 2025
School of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang, China.
The incidence of acute myeloid leukemia (AML) is increasing annually, and timely diagnostic and treatments can substantially improve patient survival rates. AML typing traditionally relies on manual microscopy for classifying and counting myeloid cells, which is time-consuming, laborious, and subjective. Therefore, developing a reliable automated model for myeloid cell classification is imperative.
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uHuntsman Cancer Institute (NCI-CCC), University of Utah, Salt Lake City, UT, USA.
Ther Clin Risk Manag
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National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Gaucher disease (GD) is a rare lysosomal storage disorder resulting from a deficiency of the lysosomal enzyme glucocerebrosidase caused by biallelic variants in the gene. Patients may present with a wide spectrum of disease manifestations, including hepatosplenomegaly, thrombocytopenia, bone manifestations, and in the case of GD types 2 and 3, neurodegeneration, cognitive delay, and/or oculomotor abnormalities. While there is no treatment for neuronopathic GD, non-neuronopathic manifestations can be efficiently managed with enzyme replacement therapy or substrate reduction therapy.
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January 2025
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View Article and Find Full Text PDFBMC Oral Health
January 2025
Department of Orthodontics, Afyonkarahisar Health Sciences University Faculty of Dentistry, Afyonkarahisar, Turkey.
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