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A Rare Case of a Malignant Proliferating Trichilemmal Tumor: A Molecular Study Harboring Potential Therapeutic Significance and a Review of Literature.
Dermatopathology (Basel)
December 2024
Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
Malignant proliferating trichilemmal tumors (MPTTs), arising from the external root sheath of hair follicles, are exceptionally rare, with limited documentation of their genetic alterations. We present a case of a 64-year-old African American woman who initially presented with a gradually enlarging nodule on her posterior scalp. An initial biopsy at an outside hospital suggested metastatic adenocarcinoma or squamous cell carcinoma (SCC) of an uncertain origin.
View Article and Find Full Text PDFScalp Bogginess in the Presence of Lichen Planopilaris: Isolated Occurrence or Reactionary Process?
Cureus
November 2024
Dermatology, Baylor College of Medicine, Houston, USA.
Lipedematous scalp (LS) and lipedematous alopecia (LA) are rare conditions involving focal or diffuse hyperplasia within subcutaneous adipose tissue of the scalp. Little is known regarding the etiology of these conditions, and there is no consensus on management strategies. Overall, the condition is benign and often isolated.
View Article and Find Full Text PDFDiffuse Hair Loss in a Teenage Girl: Challenge.
Am J Dermatopathol
January 2025
Department of Dermatology, Hospital Son Llàtzer, Palma de Mallorca, Spain.
Diffuse Hair Loss in a Teenage Girl: Answer.
Am J Dermatopathol
January 2025
Department of Dermatology, Hospital Son Llàtzer, Palma de Mallorca, Spain.
Case report: Fatal long-term intoxication by 2,4-dinitrophenol and anabolic steroids in a young bodybuilder with muscle dysmorphia.
Front Public Health
December 2024
Department of Legal and Penitentiary Medicine, Rennes University Hospital, Rennes, France.
A case of chronic intoxication by 2,4-dinitrophenol (2,4-DNP) is reported in a 21-year-old bodybuilder, also known as an abuser of anabolic steroids, who died after ingesting 2 grams of this substance after 6 months of repeated consumption. The bodybuilder presented the triad of symptoms - tachycardia, tachypnoea, profuse sweating - from 6 months before his death, and was hospitalised for multiple organ failure 4 months before his death. Medical staff attributed this serious episode to his consumption of 2,4-DNP.
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