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Curbside Consult Optimizing Statin Therapy in the Elderly: A Personalized Approach to Cardiovascular Disease Prevention.
Cardiol Rev
January 2025
Departments of Cardiology and Medicine, Westchester Medical Center and New York Medical College, Valhalla, NY.
Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) play a vital role in managing and preventing cardiovascular disease, particularly in elderly populations who face elevated risks for atherosclerosis and related conditions. This review delves into the mechanisms of statin action, emphasizing their impact on low-density lipoprotein cholesterol levels, anti-inflammatory properties, and potential genetic factors influencing efficacy and drug tolerability. Consideration is given to statin intolerance and management strategies, drug interactions, and guidelines for primary and secondary prevention of cardiovascular events.
View Article and Find Full Text PDFThe laws of medical malpractice have historically differed in significant ways from general liability laws. Until the mid-twentieth century, physician liability in the United States was limited to cases in which the doctor and patient had an established professional relationship. In the 1970s, courts and legislatures began carving out exceptions when patients posed an imminent threat to identifiable third parties.
View Article and Find Full Text PDFCurbside Consults Salt-Free Potassium-Enriched Substitute Versus Salt-Free Diet in Hypertension: Which Is Better?
Cardiol Rev
September 2024
Departments of Cardiology and Medicine, Westchester Medical Center and New York Medical College, Valhalla, NY.
This article examines the potential benefits of using potassium-enriched salt and following a salt-free diet to control hypertension, a prevalent global condition and a major risk factor for heart disease, stroke, and kidney disease. The article explores the impact of sodium on high blood pressure, explains what potassium-fortified salt is, and includes personal experiences. The article also examines the scientific proof backing potassium-fortified salt, evaluating its advantages and constraints.
View Article and Find Full Text PDFBackground And Objective: Inpatient subspecialty consultation is often medically necessary but in some cases may represent overuse. While pediatric consultation patterns have been described using observational data, qualitative methods may generate knowledge about contextual determinants of consultation behavior. Our objective was to understand how pediatric hospitalists make decisions about subspecialty consultation.
View Article and Find Full Text PDFDiagnostic guidelines for familial hemophagocytic lymphohistiocytosis revisited.
Blood
November 2024
Division of Bone Marrow Transplantation and Immune Deficiency, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Article Synopsis
- The study analyzed the current diagnostic criteria for familial hemophagocytic lymphohistiocytosis (FHL) and aimed to improve them through a case-control approach involving 366 children with genetic FHL or Griscelli syndrome.
- It compared the existing HLH-2004 criteria's effectiveness with a new optimal model based on 17 variables, finding similar diagnostic thresholds with high accuracy rates (99.1% overall).
- The researchers concluded that while the HLH-2004 criteria are valid, additional cellular and genetic assays are beneficial for confirming diagnoses, particularly in differentiating FHL from severe infections or systemic-onset juvenile idiopathic arthritis.
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