Pulmonary metastases from an Ameloblastoma: case report and review of the literature.

J Craniomaxillofac Surg

Department of Stomatology, The Frist Affiliated Hosptial, Sun Yat-Sen University, Guangzhou, Guangdong 510080, People's Republic of China.

Published: December 2012

AI Article Synopsis

  • Ameloblastomas are tumors known for high recurrence rates and local invasion, classifying them as borderline tumors, but they rarely metastasize.
  • A case study details a patient whose mandibular ameloblastoma came back 29 years after surgery and metastasized to both lungs, making complete surgical removal impossible.
  • The pulmonary metastases were confirmed via biopsy and not actively treated; monitoring over four years showed no significant changes in the lung tumors, while recent cases are reviewed regarding their occurrence and treatment.

Article Abstract

Ameloblastomas have a high recurrence rate, and because of their biological tendency towards local invasion are considered borderline tumours. Despite this, reports of metastasis of these tumours are rare. This report presents a patient with mandibular ameloblastoma that recurred 29 years after surgery and metastasized to both lungs. Because of the large range of the area of metastasis, complete surgical resection of the tumours was impossible. After confirming the diagnosis by biopsy of the pulmonary lesions the pulmonary metastases were not treated actively. Observation over 4 years showed no obvious change in the lung metastasis. Recent cases are summarized and analyzed in this paper, with respect to its occurrence, pathological types, methods of treatment and other related aspects.

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http://dx.doi.org/10.1016/j.jcms.2012.03.006DOI Listing

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