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Efficacy and Safety of Cardiac Myosin Inhibitors in Hypertrophic Cardiomyopathy: A Meta-Analysis of Randomized Controlled Trials.
Cardiol Rev
October 2024
Department of Cardiology, Royal Devon University Healthcare National Health Service Foundation Trust, Exeter, United Kingdom.
Hypertrophic cardiomyopathy (HCM) is a genetic cardiac disorder characterized by structural and functional abnormalities. Current management strategies, such as medications and septal reduction therapies, have significant limitations and risks. Recently, cardiac myosin inhibitors (CMIs) like mavacamten and aficamten have shown promise as noninvasive treatment options.
View Article and Find Full Text PDFVisceral Fat Affects Heart Rate Recovery but Not the Heart Rate Response Post-Single Bout of Vigorous Exercise: A Cross-Sectional Study in Non-Obese and Healthy Participants.
Sports (Basel)
November 2024
Department of Biomedical and Biotechnological Sciences, Section of Anatomy, Histology and Movement Science, School of Medicine, University of Catania, Via S. Sofia n°97, 95123 Catania, Italy.
Body composition could influence exercise physiology. However, no one has ever studied the effect of visceral fat (VF) on heart rate (HR) trends during and after exercise by using bioimpedance analysis (BIA). This study aims to investigate BIA variables as predictors of HR trends during vigorous exercise.
View Article and Find Full Text PDFOlympic distance duathlon and cardiac performance in highly-trained triathletes.
Physiol Rep
December 2024
Department of Cardiology, St George's University Hospitals NHS Foundation Trust, London, UK.
The effects of triathlon exercise on cardiac function are well documented. While Olympic triathlon (swim-bike-run) remains the standard format, increasing concerns about water quality in natural waterways present ongoing challenges for open-water swimming events, highlighting the potential need to consider alternative formats such as duathlon (run-bike-run) in some circumstances. An additional run may increase the overall metabolic and cardiovascular demand compared with the swim in triathlon, leading to reduced future performance.
View Article and Find Full Text PDFEffect of respiration and exercise on seismocardiographic signals.
Comput Biol Med
December 2024
Department of Mechanical and Aerospace Engineering, University of Central Florida, and the Biomedical Acoustics Research Company, 32816, Orlando, FL, USA.
Background: Seismocardiographic signals (SCG) are chest wall vibrations induced by mechanical cardiac activities. This study investigated the morphological changes in the SCG signal due to respiration and exercise.
Methods: Fifteen healthy subjects were recruited, and SCG was acquired before and after exercise.
Effects of physical exercise on cardio-respiratory health of young adults during short-term exposure to varying air pollution levels.
BMC Public Health
December 2024
School of Exercise and Health, Shanghai University of Sport, Yangpu District Qingyuan Huan Road 650, Shanghai, 200438, China.
Background: Air pollution (AP) has become a substantial environmental issue affecting human cardiorespiratory health. Physical exercise (PE) is widely accepted to promote cardiorespiratory health. There is a paucity of research on the point at which the level of polluted environment engaged in PE could be used as a preventive approach to compensate for the damages of AP.
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