Objective: To investigate factors associated with latent syphilis and pregnancy outcome among women with latent syphilis.
Methods: A retrospective population-based study was conducted to compare all pregnancies among women with and without latent syphilis at Soroka University Medical Center, Be'er-Sheva, Israel, between 1988 and 2010. Stratified analysis using a multiple logistic regression model was performed to control for confounders.
Results: Of the 219656 deliveries during the study period, 159 (0.1%) involved women with latent syphilis. Multivariate analysis with backward elimination revealed the following conditions to be significantly associated with latent syphilis: fetal growth restriction (odds ratio [OR] 2.20; 95% confidence interval [CI], 1.07-4.49; P=0.03); drug abuse (OR 9.95; 95% CI, 1.31-75.46; P=0.02); tobacco use (OR 3.35; 95% CI, 1.74-6.45; P<0.05); and Jewish (vs Bedouin) ethnicity (OR 4.05; 95% CI, 2.65-6.20; P<0.05).
Conclusion: Women with latent syphilis are at risk for adverse maternal and perinatal outcomes, including fetal growth restriction. Careful surveillance of these high-risk pregnancies should be considered.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ijgo.2012.01.026 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Multidisciplinary Approach of a Male Case of Imported Malaria, HIV Chronic Infection, and Latent Syphilis.
Infect Dis Rep
November 2024
Hospital Juárez de México, Mexico City 07760, Mexico.
Background: The current economic and social crisis in Latin America has caused migration to the USA, bringing with it Public Health challenges due to the importation of various infectious diseases. Migrants, particularly those with chronic conditions, such as HIV infection and other sexually transmitted infections (STI), are at greater risk due to pharmacological interruption and access to medical care, so the timely detection of diseases acquired during their migration, such as malaria, is crucial to avoid health complications.
Objective: To outline by a multidisciplinary approach (Infectology, Parasitology, Epidemiology, molecular Biology, Venereology, and Public Health) the diagnosis and management of a male case with malaria imported to Mexican territory, HIV chronic infection, and latent syphilis.
Endocarditis and ascending aortic aneurysm with aortic valve insufficiency secondary to late syphilis: Case report.
Sci Prog
December 2024
Cardiology and Internal Medicine Department, Fundación Clínica Shaio, Bogotá, Colombia.
Article Synopsis
- Venereal syphilis, caused by the bacteria Treponema pallidum, can escalate to serious complications like tertiary syphilis, which affects the heart decades after the initial infection.
- A case study highlights a 46-year-old woman who developed life-threatening cardiac issues, including an ascending aortic aneurysm and severe aortic valve damage, due to untreated late-stage syphilis.
- She underwent surgery to repair her aorta and replace the damaged valve, receiving antibiotics and intensive care; her recovery was satisfactory with no complications reported three months later.
Secondary Syphilis in the Spotlight: Atypical Cutaneous Manifestation Overshadowing Kaposi Sarcoma in a Newly Diagnosed HIV Patient.
Cureus
October 2024
Pathology, Hospital Universitario "Dr. José Eleuterio González", Monterrey, MEX.
Syphilis, caused by the spirochete , is a sexually transmitted infection (STI) that has seen a resurgence worldwide, particularly among populations at a higher risk of co-infection with human immunodeficiency virus (HIV). The disease typically progresses through distinct stages: primary, secondary, latent, and tertiary, each with specific clinical manifestations. Secondary syphilis is characterized by systemic involvement and various mucocutaneous symptoms, including a maculopapular rash that frequently involves the palms and soles along with fever, lymphadenopathy, and mucous membrane lesions.
View Article and Find Full Text PDFA Loop-Mediated Isothermal Amplification Assay Utilizing Hydroxy Naphthol Blue (LAMP-HNB) for the Detection of Subspp. .
Pathogens
October 2024
Faculty of Medicine, Srinakharinwirot University, Bangkok 10110, Thailand.
subspp. is a spirochaete bacterium that causes syphilis, one of the most common sexually transmitted diseases. Syphilis progresses through four distinct stages, each characterized by specific symptoms, namely primary, secondary, latent, and late (tertiary) syphilis.
View Article and Find Full Text PDFJudicious Use of Benzathine Penicillin G in Response to a Medication Alert During a Critical Drug Shortage.
J Pharm Technol
October 2024
Department of Pharmacy, Henry Ford Hospital, Detroit, MI.
Purpose: To evaluate judicious antibiotic prescribing of benzathine penicillin G (BPG) after implementation of an electronic health record-based medication shortage alert during a critical drug shortage.
Methods: This was an institutional review board-approved retrospective cohort study of patients aged ≥3 months who received BPG between May 9, 2023, and February 28, 2024. The study included inpatient and outpatient visits after implementing a BPG medication shortage alert; patients with severe penicillin allergy, neurosyphilis, or congenital syphilis were excluded.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!