Optimized serodiagnosis of Mycoplasma pneumoniae infections.

Diagn Microbiol Infect Dis

Institute of Medical Microbiology and Hygiene, Dresden University of Technology, Fetscherstrasse 74, Dresden, Germany.

Published: June 2012

Serologic methods are well established for the diagnosis of Mycoplasma pneumoniae infections in humans, but they are less sensitive than polymerase chain reaction (PCR). To improve their sensitivity, a new panel of antigens was tested. Compared with PCR results, up to 92% of PCR-positive patients were confirmed by our immunoblotting approach having a specificity between 92.6% and 100%.

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http://dx.doi.org/10.1016/j.diagmicrobio.2012.02.014DOI Listing

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