Issue Addressed: Preventing childhood poisoning is an important injury-control priority, requiring a multi-strategy approach. However, there remains a wide void between what is recommended by prevention programs and the evidence, and what is acted upon in the day-to-day family environment. This paper seeks to probe behind aspects of this void by examining parental perceptions in relation to childhood poisoning within a Health Belief Model framework.
Methods: Data were collected through telephone interviews from 200 randomly selected Western Australian parents/guardians of children aged 0-4 years.
Results: The uptake of poisoning prevention strategies was associated with the perceived susceptibility and seriousness of poisoning from different common household products. In particular, those products considered most fatally poisonous (workshop/garden chemicals) and a common cause of childhood poisoning were the most likely to be locked up and kept out of reach of children. Conversely, over-the-counter medicines were not considered by the majority of parents as fatally poisonous or as a common cause of poisoning, and were less likely to be locked up and placed out of reach. However, such medicines are the most common cause of unintentional childhood poisoning.
Conclusion: The results suggest that perceptions of susceptibility and seriousness need to be targeted as part of efforts to encourage parents to reduce household risks of childhood poisoning. This is particularly warranted in relation to those common household products (e.g. medicines) where there is a misperception of lower likelihood of serious poisoning occurring.
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http://dx.doi.org/10.1071/he11217 | DOI Listing |
JMIR Form Res
January 2025
Center on Substance Use and Health, San Francisco Department of Public Health, San Francisco, CA, United States.
Background: Despite increasing fatal stimulant poisoning in the United States, little is understood about the mechanism of death. The psychological autopsy (PA) has long been used to distinguish the manner of death in equivocal cases, including opioid overdose, but has not been used to explicitly explore stimulant mortality.
Objective: We aimed to develop and implement a large PA study to identify antecedents of fatal stimulant poisoning, seeking to maximize data gathering and ethical interactions during the collateral interviews.
Arch Dis Child
January 2025
Pediatric Emergency Department, Cruces University Hospital Paediatric Emergencies, Barakaldo, Spain
Introduction: Although the administration of activated charcoal (AC) is considered safe, the associated risk of pulmonary aspiration explains certain reluctance of physicians to use this procedure. The objective of this study was to analyse the rate of pulmonary aspiration in children receiving AC after accidental ingestion of a toxic substance.
Methods: We carried out a substudy of a multicentre prospective registry-based cohort study including children presenting with acute poisoning to 58 paediatric emergency department (EDs) members of the Spanish Society of Pediatric Emergency Medicine between 2008 and 2022 on certain previously designated days.
Bedřich Smetana's illness associated with complete hearing loss has been linked to various diseases in a long-running discussion. Senile dementia, atherosclerosis, progressive paralysis in lues are mentioned, while the ototoxicity of mercury is neglected. Its high concentration in the composer's skeletal remains was demonstrated by the authors of this article immunohistochemically and especially by the neutron activation analysis (NAA) method 23 years ago.
View Article and Find Full Text PDFPharmacotherapy
January 2025
Texas Children's Cancer and Hematology Centers, Houston, Texas, USA.
Background: Methotrexate is an important component of curative therapy in childhood acute lymphoblastic leukemia (ALL), but the role of genetic variation influencing methotrexate clearance and transport in toxicity susceptibility in children with ALL is not well established. Therefore, we evaluated the association between suspected methotrexate pharmacogenomic variants and methotrexate-related neurotoxicity.
Methods: This study included children (aged 2-20 years) diagnosed with ALL (2005-2019) at six treatment centers in the southwest United States.
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