The aim of this study was to evaluate facial morphology in 25 Class III and 46 non-Class III children aged 5-6 years using three-dimensional (3D) laser imaging; 3D facial images were obtained, two average facial templates were constructed for the non-Class III male and female groups, each individual face was superimposed on the corresponding average template and group comparisons were evaluated (facial height, facial convexity, mandibular position and facial surface morphology). Differences between parameters were evaluated by using an analysis of variance and colour deviation maps. The results showed that Class III children had less mid-face prominence and a concave facial profile when compared to non-Class III children (P = 0.002 and P = 0.018). The position of the pg point in the z-axis just failed to reach statistical significance when comparing the two groups (P = 0.051). A vertical analysis showed no statistical significance between the groups, when evaluating middle (n-sn) and lower (sn-pg) facial height. Coincidence of the Class III faces to normal templates with a tolerance set as 0.5 mm was low (less than 30%). The soft tissue characteristics of a Class III face differ significantly from the non-Class III face in the mid-face region and in the facial profile. A 3D laser imaging method evaluated and identified morphological characteristics of Class III children in deciduous dentition, which could in the future become an important diagnostic tool in small children. The most important clinical advantage of this study is the non-invasiveness of the method.
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http://dx.doi.org/10.1093/ejo/cjs018 | DOI Listing |
Neurology
February 2025
Genomics of Neurodegenerative Diseases and Aging, Human Genetics, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, the Netherlands.
Background And Objectives: Identifying genetic causes of dementia in patients visiting memory clinics is important for patient care and family planning. Traditional clinical selection criteria for genetic testing may miss carriers of pathogenic variants in dementia-related genes. This study aimed identify how many carriers we are missing and to optimize criteria for selecting patients for genetic counseling in memory clinics.
View Article and Find Full Text PDFMatern Child Nutr
January 2025
Department of Nursing, Faculty of Health Sciences, University of Alicante, San Vicente del Raspeig, Spain.
Parental feeding styles are an important factor influencing child development. Traditionally, they have been classified into four styles based on cut-off points for responsiveness and demandingness. However, alternative methods, such as latent class analysis (LCA), allow for the detection of underlying homogeneous populations.
View Article and Find Full Text PDFUrogynecology (Phila)
January 2025
From the Division of Urogynecology, Department of OB/GYN, Harbor-UCLA Medical Center, Torrance, CA.
Importance: Stress urinary incontinence (SUI) affects approximately 50% of women. There are limited data regarding trends in management as treatment options have changed.
Objective: This study aimed to analyze trends in the surgical management of SUI, including slings and urethral bulking, from 2012 to 2022.
Endocrinol Diabetes Metab Case Rep
January 2025
Summary: Oral levothyroxine (LT4) is prescribed worldwide for hypothyroidism. Bariatric surgery for patients with obesity has shown a substantial, long-term weight loss and considerable improvement of obesity-related diseases. LT4 malabsorption represents a significant cause of refractory hypothyroidism, well known after malabsorptive bariatric surgery such as Roux-en-Y gastric bypass.
View Article and Find Full Text PDFDalton Trans
January 2025
Department of Chemistry and Biochemistry, Auburn University, Auburn, AL 36849, USA.
Although nickel is found in the active sites of a class of superoxide dismutase (SOD), nickel complexes with non-peptidic ligands normally do not catalyze superoxide degradation, and none has displayed activity comparable to those of the best manganese-containing SOD mimics. Here, we find that nickel complexes with polydentate quinol-containing ligands can exhibit catalytic activity comparable to those of the most efficient manganese-containing SOD mimics. The nickel complexes retain a significant portion of their activity in phosphate buffer and under operando conditions and rely on ligand-centered redox processes for catalysis.
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