Introduction: Laparoscopy during pregnancy is safe and effective, but poses unique challenges because of alterations in the intra-abdominal anatomy induced by the gravid uterus.
Case: A 33-year-old female with an intrauterine pregnancy at 19 weeks' gestation presented with symptoms of appendicitis. Diagnostic laparoscopy resulted in incidental uterine perforation and insufflation. Transition to midline laparotomy was made to suture uterine puncture sites from the trocar and Veress needle. Preterm premature rupture of membranes and abruption were diagnosed at 32 weeks' gestation, and the patient was delivered. The child was alive and well at 12 months of age.
Conclusions: Lessons from the emerging field of minimally invasive fetal surgery regarding the management of surgical entry into the gravid uterus can be applied to the rare case of incidental uterine perforation at the time of laparoscopy during pregnancy.
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http://dx.doi.org/10.1097/SLE.0b013e318243a494 | DOI Listing |
BMC Pregnancy Childbirth
January 2025
Department of Gynecology, Shenyang Women's and Children's Hospital, No. 87 Renao Road, Shenyang, Liaoning Province, 110011, China.
Background: This study aimed to investigate the risk factors related to the failure of initial combined local methotrexate (MTX) treatment and minimally invasive surgery for late cesarean scar pregnancy (CSP).
Methods: This retrospective case-control study was conducted between January 2016 and December 2023, involving patients with late CSP (≥ 8 weeks) who received local MTX injection combined with either hysteroscopic or laparoscopic surgery. Cesarean scar pregnancy was classified as type I, II, or III based on the direction of growth of the gestational sac and the residual myometrial thickness as assessed by ultrasound.
Int J Surg Case Rep
January 2025
Department of General Surgery, Kamanga Medics Hospital, P.O. Box 5228, Mwanza, Tanzania.
Introduction: Appendicitis in pregnancy is the most common non-obstetric surgical condition which requires urgent evaluation and immediate intervention in a multidisciplinary approach. Pregnancy anatomical and physiological changes can mask the presentation of appendicitis and poses both diagnostic and management challenges.
Case Presentation: A 32 year old female, G3P2L2 at gestation age of 11 weeks by USS, presented with recurrent episodes of acute abdominal pain for one day, afebrile but accompanied with poor appetite, nausea and vomiting along episodes of per vaginal spotting which started three days prior.
Hum Reprod
January 2025
IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III-Paul Sabatier (UPS), Toulouse, France.
Study Question: Does a human fallopian tube (HFT) organoid model offer a favourable apical environment for human sperm survival and motility?
Summary Answer: After differentiation, the apical compartment of a new HFT organoid model provides a favourable environment for sperm motility, which is better than commercial media.
What Is Known Already: HFTs are the site of major events that are crucial for achieving an ongoing pregnancy, such as gamete survival and competence, fertilization steps, and preimplantation embryo development. In order to better understand the tubal physiology and tubal factors involved in these reproductive functions, and to improve still suboptimal in vitro conditions for gamete preparation and embryo culture during IVF, we sought to develop an HFT organoid model from isolated adult stem cells to allow spermatozoa co-culture in the apical compartment.
J Pediatr Surg
December 2024
Public Health School, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
Background And Aims: Benign ovarian neoplasms are common in the pediatric population. In young adult women, oophorectomy has been shown to negatively impact long-term ovarian endocrine function. Recently, ovarian-sparing surgery (OSS) has been proposed as it offers similar results to oophorectomy in terms of recurrence rates.
View Article and Find Full Text PDFF S Rep
December 2024
Department of Obstetrics and Gynecology, University of Utah Health, Salt Lake City, Utah.
Objective: To determine whether endometriosis typology, namely ovarian endometriomas (OE), deep infiltrating endometriosis (DIE), or superficial endometriosis (SE), correlates with fertility history.
Design: Prospective cohort.
Setting: One of fourteen surgical centers in Salt Lake City, Utah (n = 5) or San Francisco, California (n = 9).
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