Magnetite nanoclusters (MNCs) were aligned one-dimensionally in the hollow cavity of a lipid nanotube (LNT) as a peapod using a simple mixing method in an aqueous solution. The electrostatic interaction of the two materials was considerable enough to allow the preparation of a densely packed MNC-LNT peapod composite. The composite was formed at a pH 5.4-6.8, i.e., near the isoelectric point of the MNCs. At a pH 5.4-6.8, there was neither a strong attractive nor repulsive electrostatic interaction between the surface of the MNC and the LNT. The MNCs-capped LNT composites were formed at basic conditions (above a pH 7.8) in which the MNCs and the LNT pushed each other because of their opposite surface charges. The magnetic property measurement revealed that the 1D aligned MNCs in the peapod structure had a much higher coercivity (10.6 Oe) than the bulk randomized MNCs (5.8 Oe).
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http://dx.doi.org/10.1021/am300122f | DOI Listing |
Environ Sci Pollut Res Int
December 2024
Department of Biosciences, Manipal University Jaipur, Jaipur, 303007, Rajasthan, India.
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School of Chemical Engineering, Sungkyunkwan University, Suwon 16419, Republic of Korea.
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Institut Curie, Université PSL, Sorbonne Université, CNRS UMR168, Laboratoire Physique des Cellules et Cancer, Paris, France.
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Transdermal drug delivery systems (TDDS) have emerged as a popular non-invasive approach for treating skin-related disorders, offering quick and reliable drug delivery into the skin, thereby accelerating therapeutic efficacy. In India, there is a growing interest in TDDS due to its perceived safety and effectiveness. Researchers are actively developing new formulations and technologies to enhance drug delivery efficiency and reduce side effects.
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