AI Article Synopsis
- Feeding a high-cholesterol diet to rats that included a water-soluble peanut skin polyphenol fraction led to a decrease in their plasma cholesterol levels.
- The study found that lower-molecular-weight polyphenols were more effective in reducing cholesterol than higher-molecular-weight ones.
- This cholesterol-lowering effect may be linked to certain oligomeric polyphenols that hinder the solubility of dietary cholesterol in the gut.
Article Abstract
Feeding a high-cholesterol diet with a water-soluble peanut skin polyphenol fraction to rats reduced their plasma cholesterol level, with an increase in fecal cholesterol excretion. The hypocholesterolemic effect was greater with the lower-molecular-weight rather than higher-molecular-weight polyphenol fraction. This effect was possibly due to some oligomeric polyphenols which reduced the solubility of dietary cholesterol in intestinal bile acid-emulsified micelles.
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| http://dx.doi.org/10.1271/bbb.110866 | DOI Listing |
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