AI Article Synopsis
- The study identifies key risk and prognostic factors that can predict anastomotic leakage in colorectal resections for cancer patients.
- A total of 1,743 patients were analyzed, revealing that 54 experienced anastomotic leaks, correlating this complication with pre-existing health issues like hypoproteinemia and anemia.
- The findings suggest that low serum protein levels and hemoglobin can serve as significant predictive markers for anastomotic leak potential.
Article Abstract
Purpose: To identify the risk and prognosis factors and their predictive value for anastomotic leakage after colorectal resections following cancer.
Patients And Methods: 1743 consecutive patients who underwent colic resections or rectal resections for colo-rectal cancer between 1996-2005 in Surgical Clinic no. 3 (Cluj-Napoca, Romania) were retrospectively analysed.
Results: A total of 54 (3.09 percent) anastomotic leaks were confirmed. Univariate analisys showed that the preoperative variables significantly associated with anastomotic leakage included weight loss, smoking, cardiovascular disease, lung disease, hypoproteinemia, diabetes, anemia, leukocitosis, presence of two or more underlying diseases. Use of alcohol, cerebrovascular disease, bowel preparation, mode of antibiotic prophylaxis, type of handsewn anastomosis, tumor location, tumor stage and tumor histology were nonsignificant variables. Hipoproteniemia (S - proteins < 60g/dl) and anemia (S Hb < 11) remained significant in logistic regression model.
Conclusions: Our study shows that a value of S-proteins lower than 60 g/l and s-Hb lower than 99 g/l can be consider as predictive marker for anastomotik leak deshiscence.
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