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Intrapleural injection of OK-432 as the primary in-utero treatment for fetal chylothorax. | LitMetric

Intrapleural injection of OK-432 as the primary in-utero treatment for fetal chylothorax.

Hong Kong Med J

Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong.

Published: April 2012

Chylothorax is a rare congenital condition associated with significant perinatal mortality and morbidity. Previous treatments with repeated thoracocentesis or thoracoamniotic shunting were technically demanding, and associated with significant procedure-related complications and neonatal complications. Here we report the first successful case in Hong Kong treated by a simple and effective intervention, namely pleurodesis with OK-432, in a fetus presenting at 20 weeks of gestation with bilateral pleural effusion.

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