AI Article Synopsis

  • The study evaluated whether Proton Pump Inhibitor (PPI) prescriptions in hospitalized patients followed Clinical Practice Guidelines (CPG) at two academic hospitals in Lima.
  • Over 54% of PPI prescriptions were not aligned with CPG, particularly in the General Surgery department where 83.6% were inappropriate.
  • The primary valid reason for PPI use in line with CPG was the prevention of NSAID-induced gastric ulcers in elderly patients (65.72%).

Article Abstract

Objectives: To evaluate if Proton Pump Inhibitor (PPI) prescription is based in Clinical Practice Guidelines (CPG) in hospitalized patients at two academic hospitals of Lima.

Materials And Methods: The services of Intern Medicine, Tropical Medicine and General Surgery were visited. Therapeutic sheets and nursing transcript were checked. The prescription motifs were determined in patients who received PPI. These motifs were obtained according to a check list, which was made from different CPG.

Results: 54.57% of the PPI prescriptions in the two academic hospitals were not based in CPG. No statistic significant difference was found between the two academic hospitals in the PPI prescription based in CPG (p=0,208). Most of the prescriptions not base on CPG belong to the service of General Surgery (83.6%; p<0.0001). The main indication for the prescription of PPI based on CPG was prevention of NSAIDS induced gastric ulcers if advanced age (65.72%).

Conclusions: There is a high rate of PPI overuse in two academic hospitals.

Download full-text PDF

Source

Publication Analysis

Top Keywords

academic hospitals
16
prescription based
12
proton pump
8
pump inhibitor
8
based clinical
8
clinical practice
8
practice guidelines
8
hospitalized patients
8
patients academic
8
ppi prescription
8

Similar Publications

Protocol for recording physiological signals from the human cerebellum using electroencephalography.

STAR Protoc

January 2025

Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA; Initiative for Columbia Ataxia and Tremor, Columbia University, New York, NY 10032, USA. Electronic address:

As Purkinje cells of the cerebellum have a very fast firing rate, techniques with high temporal resolution are required to capture cerebellar physiology. Here, we present a protocol to record physiological signals in humans using cerebellar electroencephalography (cEEG). We describe steps for electrode placement and recording.

View Article and Find Full Text PDF

Background: Respiratory syncytial virus (RSV) is an important cause of lower respiratory tract infection, hospitalisation and death in adults.

Methods: Based on evidence regarding the impact of RSV on adult populations at risk for severe infection and the efficacy and safety of RSV vaccines, the Portuguese Society of Pulmonology, the Portuguese Association of General and Family Medicine, the Portuguese Society of Cardiology, the Portuguese Society of Infectious Diseases and Clinical Microbiology, the Portuguese Society of Endocrinology, Diabetes and Metabolism, and the Portuguese Society of Internal Medicine endorses this position paper with recommendations to prevent RSV-associated disease and its complications in adults through vaccination.

Conclusion: The RSV vaccine is recommended for people aged ≥50 years with risk factors (chronic obstructive pulmonary disease, asthma, heart failure, coronary artery disease, diabetes, chronic kidney disease, chronic liver disease, immunocompromise, frailty, dementia, and residence in a nursing home) and all persons aged ≥60 years.

View Article and Find Full Text PDF

Background: Crohn's disease (CD) is a chronic, recurrent gastrointestinal disorder characterized by a complex etiology. Among its perianal complications, anal fistulas represent a challenging comorbidity. With the increase of surgical options, a comprehensive bibliometric analysis was deemed necessary to consolidate the vast array of research in this field.

View Article and Find Full Text PDF

The underlying mechanisms of the association of bone health with depression - an experimental study.

Mol Biol Rep

January 2025

Medical Sociology and Psychobiology, Department of Health and Physical Activity, University of Potsdam, 14469, Potsdam, Germany.

Background: Depression constitutes a risk factor for osteoporosis, but underlying molecular and cellular mechanisms are not fully understood. MiRNAs influence gene expression and are carried by extracellular vesicles (EV), affecting cell-cell communication.

Aims: (1) Identify the difference in miRNA expression between depressed patients and healthy controls; (2) Analyze associations of these miRNAs with bone turnover markers; (3) Analyze target genes of differentially regulated miRNAs and predict associated pathways regarding depression and bone metabolism.

View Article and Find Full Text PDF

Sleep is influenced by various factors, including social, economic, genetic, and medical factors, and work and study schedules. Medical students are highly susceptible to sleep-related problems. In this study, we aimed to evaluate the sleep patterns and quality of medical students and determine their correlation with academic achievement.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!