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Longitudinal trends and predictors of limitations in activities of daily living in community-dwelling older adults: evidence from the KLoSA study.
Front Public Health
December 2024
College of Nursing, Hanyang University, Seoul, Republic of Korea.
Background: As life expectancy increases, the number of older adults with functional limitations is also increasing. Functional limitations are associated with adverse health outcomes such as reduced independence, diminished quality of life (QoL), and disability. Therefore, identifying which activities of daily living (ADLs) are limiting and understanding the influencing factors are crucial for developing tailored interventions.
View Article and Find Full Text PDFModification of gemcitabine with oxaliplatin in China for unresectable gallbladder cancer: a cost-effectiveness analysis.
Front Public Health
December 2024
Department of Pharmacy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Background: The incidence of gall bladder cancer (GBC), one of the most prevalent bile duct malignancies, differs with ethnicity and geographic location. To treat unresected GBC in the Chinese setting, this study aimed to assess the financial effectiveness of a combination of modified gemcitabine and oxaliplatin.
Methods: Data from a randomized controlled study in which individuals with metastatic GBC were treated with oxaliplatin and gemcitabine demonstrated improved survival.
The current status of trauma care for older adults in Saudi Arabia.
Front Med (Lausanne)
December 2024
Sheffield Centre for Health and Related Research, University of Sheffield, Sheffield, United Kingdom.
The aging population in Saudi Arabia presents unique challenges to the trauma care system, especially in prehospital settings. This narrative review aims to assess the current status of trauma care for older adults in Saudi Arabia, focusing on the implications of aging, gaps in the trauma system, and the role of emergency medical services. The global rise in life expectancy has increased the incidence of injuries among older adults, leading to a greater burden on healthcare systems.
View Article and Find Full Text PDFCardiovascular risks of Asian patients on androgen-receptor-targeted agents for prostate cancer: a systematic review and meta-analysis.
Prostate Int
December 2024
Department of Urology, National University Hospital, National University Health System, Singapore.
Background: Prostate cancer is now one of the most prevalent cancers in men in Asia. As the average life expectancy of Asian males with prostate cancer increases with the availability of treatment options, the possible risk of cardiac-related adverse effects arising from androgen-receptor-targeted agents (ARTAs) may be increased due to the greater exposure. We aim to perform a meta-analysis on the incidence of cardiac-related adverse events in Asian patients with prostate cancer treated with ARTAs.
View Article and Find Full Text PDFFrailty and Clinical Outcomes of Older Patients Admitted to an Emergency Department in Japan.
Cureus
November 2024
Nursing, Hokusetsu General Hospital, Osaka, JPN.
Introduction Medical advances and improved living standards have increased life expectancy, and the percentage of older adults is growing rapidly. The proportion of older adults visiting the emergency department (ED) is also increasing. Frailty is recognized as a significant risk factor for adverse outcomes.
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