Objectives: The purpose of this study was to assess the effectiveness of a novel radiation-independent aiming device for distal locking of intramedullary nails in a human cadaver model.
Methods: A new targeting system was used in 25 intact human cadaver femora for the distal locking procedure after insertion of an intramedullary nail. The number of successful screw placements and the time needed for this locking procedure were recorded. The accuracy of the aiming process was evaluated by computed tomography.
Results: The duration of the distal locking process was 8.0 ± 1.8 minutes (mean ± SD; range, 4-11 minutes). None of the screw placements required fluoroscopic guidance. Computed tomography revealed high accuracy of the locking process. The incidence angle (α) of the locking screws through the distal locking holes of the nail was 86.8° ± 5.0° (mean ± SD; range, 80°-96°). Targeting failed in 1 static locking screw because of a material defect in the drilling sleeve.
Conclusions: This cadaver study indicated that an aiming arm-based targeting device is highly reliable and accurate. The promising results suggest that it will help to decrease radiation exposure compared with the traditional "free-hand technique."
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http://dx.doi.org/10.1097/BOT.0b013e318242d8b7 | DOI Listing |
Arch Orthop Trauma Surg
January 2025
Department of Orthopaedics, Wright State University, 30 E Apple St., Suite 2200, Dayton, OH, 45409, USA.
Introduction: We propose and assess the biomechanical stability of medial column screw supplementation in a synthetic distal femur fracture model.
Materials And Methods: Twenty-four low density synthetic femora modeling osteoporotic, intraarticular distal femur fractures with medial metaphyseal comminution were split into two fixation groups: (1) lateral locking distal femur plate (PA- plate alone) and (2) lateral locking distal femur plate with a 6.5 mm fully threaded medial cannulated screw (PWS- plate with screw).
J Bone Joint Surg Am
October 2024
Department of Orthopaedics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Background: Fixation of distal femoral fractures remains a challenge, and nonunions are common with standard constructs. Far cortical locking (FCL) constructs have been purported to lead to improved fracture-healing as compared with that achieved with traditional locking bridge plates. We sought to test this hypothesis in a comparative effectiveness clinical trial.
View Article and Find Full Text PDFNat Microbiol
January 2025
Department of Molecular Microbiology, John Innes Centre, Norwich, UK.
Examples of long-range gene regulation in bacteria are rare and generally thought to involve DNA looping. Here, using a combination of biophysical approaches including X-ray crystallography and single-molecule analysis for the KorB-KorA system in Escherichia coli, we show that long-range gene silencing on the plasmid RK2, a source of multi-drug resistance across diverse Gram-negative bacteria, is achieved cooperatively by a DNA-sliding clamp, KorB, and a clamp-locking protein, KorA. We show that KorB is a CTPase clamp that can entrap and slide along DNA to reach distal target promoters up to 1.
View Article and Find Full Text PDFOrthop Traumatol Surg Res
January 2025
Ankara University Faculty of Medicine, Orthopaedics and Traumatology Department, Hand Surgery Unit, Ankara, Turkey.
Introduction: Although there is no consensus in the literature, it is believed that the Soong classification system and fracture pattern are risk factors for plate removal in distal radius fractures.
Hypothesis: The aim of this large-scale study was to evaluate the relationship between Soong classification, fracture pattern, and implant removal in distal radius fractures.
Materials And Methods: We retrospectively evaluated 795 patients who underwent surgery using a volar locking plate for distal radius fractures at our clinic between 2005 and 2022.
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