We describe the usefulness of thallium-201 SPECT in a patient with neoplastic meningitis (NM) from gastric carcinoma. Thallium-201 SPECT is of value for the diagnosis of cancer; retention of thallium-201 on delayed images strongly suggests malignancy. NM is a lethal, major neurologic complication of cancer. The standard for the diagnosis of NM is cytologic confirmation of malignant cells in CSF, but cytologic results are often negative (estimated false negative rate, 50%), even when NM is strongly suspected clinically. In patients with equivocal findings, our findings suggest that thallium-201 SPECT is one helpful tool for the detection of NM, particularly when associated with signet-ring cell carcinoma.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303303 | PMC |
| http://dx.doi.org/10.3941/jrcr.v3i4.157 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Thallium-201 single photon emission computed tomography for the differentiation of malignant versus non-malignant intracranial space-occupying lesions in developing countries.
Curr Probl Cancer
December 2024
Department of Neurosciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines; Institute for Neurosciences, St. Luke's Medical Center, Quezon City & Global City, Philippines.
Background: Thallium-201 single-photon emission computed tomography (TI-SPECT) imaging has been used historically to distinguish malignant cerebral neoplasms from infectious etiologies.
Objectives: Our study aims to conduct a retrospective study, review existing literature, and perform meta-analysis on the use of TI-SPECT to differentiate malignant from non-malignant nervous system lesions when other advanced imaging modalities are not available, such as in resource-limited setting.
Methods: A retrospective study on the use of TI-SPECT in differentiating malignant versus non-malignant nervous system lesions was conducted in two tertiary hospitals in the Philippines.
Comparing the Performance of Scatter Correction Methods in Cardiac SPECT Imaging with Technetium-99m and Thallium-201 Radioisotopes.
J Med Phys
September 2024
Department of Physics, Faculty of Science, University of Mohaghegh Ardabili, Ardabil, Iran.
Purpose: This study aims to evaluate the performance of dual-energy window (DEW) and triple-energy window (TEW) scatter correction methods in cardiac SPECT imaging with technetium-99m (Tc-99m) and thallium-201 (Tl-201) radioisotopes.
Materials And Methods: The SIMIND Monte Carlo program was used to simulate the imaging system and produce the required projections. Two phantoms, including the simple cardiac phantom and the NCAT phantom, were used to evaluate the scatter correction methods.
Clinical Feasibility of Deep Learning-Based Attenuation Correction Models for Tl-201 Myocardial Perfusion SPECT.
Clin Nucl Med
May 2024
Department of Nuclear Medicine and Molecular Imaging, Ajou University School of Medicine, Suwon, South Korea.
Purpose: We aimed to develop deep learning (DL)-based attenuation correction models for Tl-201 myocardial perfusion SPECT (MPS) images and evaluate their clinical feasibility.
Patients And Methods: We conducted a retrospective study of patients with suspected or known coronary artery disease. We proposed a DL-based image-to-image translation technique to transform non-attenuation-corrected images into CT-based attenuation-corrected (CT AC ) images.
R-R' interval in the left bundle branch block predicts long-term outcomes after cardiac resynchronization therapy by estimating greater mechanical dyssynchrony and viable myocardium.
Heart Rhythm
April 2024
Department of Cardiology and Clinical Examination and Diagnosis, Faculty of Medicine, Oita University, Oita, Japan.
Background: Typical left bundle branch block (LBBB) shows 2 peaks of the R wave, which reflect activation reaching the interventricular septum (R) and posterolateral wall (R') sequentially.
Objective: The purpose of this study was to investigate the relationship among R-R' interval (RR'), mechanical dyssynchrony, extent of viable myocardium, and long-term outcomes in cardiac resynchronization therapy (CRT) candidates.
Methods: The study enrolled 49 patients (34 men; mean age: 69 ± 11 years) with LBBB who received CRT.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!