Health physics is an important discipline with regard to understanding the effects of radiation on human health. This paper aims to illustrate the unique challenges presented to the health physicist or analyst of radiological data in a large-scale emergency.
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Recommendations for reporting and evaluating proton therapy beyond dose and constant relative biological effectiveness.
Phys Imaging Radiat Oncol
January 2025
Center for Proton Therapy, Paul Scherrer Institute, Villigen PSI, Switzerland.
Background And Purpose: In proton therapy, a relative biological effectiveness (RBE) of 1.1 is used to convert proton dose into an equivalent photon dose. However, RBE varies with tissue type, fraction dose, and beam quality parameters beyond dose such as linear energy transfer (LET) raising concerns about increased local effectiveness and potential toxicity.
View Article and Find Full Text PDFA framework for the simulation of individual glycan coordinates to analyze spatial relationships within the glycocalyx.
Front Cell Dev Biol
January 2025
Department of Physics, Faculty of Sciences, FAU Erlangen-Nuremberg, Erlangen, Germany.
The glycocalyx is a dense and dynamic layer of glycosylated species that covers every cell in the human body. It plays crucial roles in various cellular processes in health and disease, such as cancer immune evasion, cancer immune therapy, blastocyst implantation, and functional attenuation of membrane protein diffusion. In addition, alterations in glycocalyx structure may play an important role in ocular surface diseases, e.
View Article and Find Full Text PDFPositive end-expiratory pressure increases intracranial pressure but not pressure reactivity index in supine and prone positions: a porcine model study.
Front Med (Lausanne)
January 2025
Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway.
Introduction: Positive end-expiratory pressure (PEEP) and prone positioning can improve gas exchange by promoting uniform lung aeration. However, elevated ventilation pressures may increase intracranial pressure (ICP) and disrupt cerebral autoregulation. This study investigated the effects of PEEP on ICP and cerebral autoregulation in a porcine model with healthy lungs and normal ICP, comparing prone and supine positions.
View Article and Find Full Text PDFPatient Experience Regarding Medication-Related Information Received in a Rural Private Polyclinic Setting in Vietnam.
J Patient Exp
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Department of Health Organization and Management, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam.
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View Article and Find Full Text PDFMetallomic Classification of Pulmonary Nodules Using Blood by Deep-Learning-Boosted Synchrotron Radiation X-ray Fluorescence.
Environ Health (Wash)
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CAS-HKU Joint Laboratory of Metallomics on Health and Environment, & CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, & Beijing Metallomics Facility, & National Consortium for Excellence in Metallomics, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China.
Ambient air pollution is an important contributor to increasing cases of lung cancer, which is a malignant cancer with the highest mortality among all cancers. It primarily manifests in the form of pulmonary nodules, but not all will develop into lung cancer. Therefore, it is highly desired to distinguish between benign and malignant pulmonary nodules for the early prevention and treatment of lung cancer.
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