A recent epidemic of malaria in the highlands of Bolivia and establishment of multiple Anopheles species mosquitoes in the highlands of Ecuador highlights the reemergence of malaria in the Andes Mountains in South America. Because malaria was endemic to many highland valleys at the beginning of the 20th century, this review outlines the 20th century history of malaria in the highlands of Ecuador, and focuses on its incidence (e.g., geographic distribution) and elimination from the northern highland valleys of Pichincha and Imbabura and the role of the Guayaquil to Quito railway in creating highland larval habitat and inadvertently promoting transportation of the vector and parasite. Involvement of control organizations in combating malaria in Ecuador is also outlined in a historical context.
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http://dx.doi.org/10.3201/eid1804.111267 | DOI Listing |
PLoS Negl Trop Dis
January 2025
ISGlobal, Barcelona, Spain.
Background: The Lihir Islands of Papua New Guinea, located in an area with high burden of malaria and hosting a large mining operation, offer a unique opportunity to study transmission. There, we investigated human and vector factors influencing malaria transmission.
Methods: In 2019, a cross-sectional study was conducted on 2,914 individuals assessing malaria prevalence through rapid diagnostic tests (RDT), microscopy, and quantitative PCR (qPCR).
PLoS One
December 2024
Department of Biology, College of Natural Sciences, Arba Minch University, Arba Minch, Ethiopia.
Parasit Vectors
December 2024
Malaria and Neglected Tropical Diseases Research Division, Armauer Hansen Research Institute, Addis Ababa, Ethiopia.
Background: Ethiopia continues to grapple with a persistent malaria burden, characterized by ongoing transmission and recurrent outbreaks. Human behavior influences both malaria exposure and the effectiveness of vector interventions, complicating malaria control efforts. Implementing tailored strategies that account for the complex interplay between human activities and vector behavior remains a challenge in both high- and low-transmission areas in Ethiopia, particularly for vulnerable highland populations and temporary labor migrants, due to lack of data.
View Article and Find Full Text PDFMalar J
December 2024
Field Epidemiology and Laboratory Training Programme, Ministry of Health, Nairobi, Kenya.
Background: Approximately 70% of the Kenyan population is at risk for malaria, including 19 million people in highland epidemic-prone and seasonal transmission areas. Surveillance data showed a 288% increase in malaria cases and an incidence rate of 10.5 per 1000 population between January and May 2021 in Nandi County.
View Article and Find Full Text PDFACS Infect Dis
December 2024
Department of Zoology, BMTC, Human Genetics and Wildlife Biology and Conservation, School of Sciences, Gujarat University, Ahmedabad, Gujarat 380009, India.
Falciparum malaria relies extensively on cell-to-cell communication, and earlier research on the function of exosomal proteins derived from infected red blood cells (iRBCs) has been classified into numerous important roles. In this study, the exosomes were derived from -iRBCs cultured in vitro during synchronized trophozoite stages. The isolated exosomes were assessed using NTA, FE-SEM, and flow cytometry.
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