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Application of the 6-SNP elevated LDL-cholesterol polygenic risk score in individuals with familial hypercholesterolemia phenotype from an Argentine population.
Gac Med Mex
January 2025
Universidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Departamento de Bioquímica Clínica, Laboratorio de Lípidos y Aterosclerosis, Ciudad Autónoma de Buenos Aires.
Introduction: LDL-cholesterol greater than 190 mg/dL indicates severe hypercholesterolemia (HS) of monogenic and/or polygenic origin. Genetic risk scores (GRS) evaluate potential polygenic causes.
Objective: we applied a GRS of 6-SNP (GRS-6) in HS individuals.
Reply to the letter "The ethics in research using data from the Instituto Nacional de Acceso a la Informacion".
Gac Med Mex
January 2024
Instituto de Investigaciones Filosóficas, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Reply to the letter "Health careers and the labor market, complex dynamics".
Gac Med Mex
January 2024
Coordinación de Universidad Abierta y Educación Digital, Innovación Educativa y Educación a Distancia, Dirección de Evaluación Educativa, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Analysis of circulating cell-free nuclear and mitochondrial DNA in plasma of Mexican patients with breast cancer.
Gac Med Mex
January 2025
División de Medicina Molecular, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social, Guadalajara.
Background: The usefulness of circulating free DNA (cfDNA), nuclear DNA (nDNA) and mitochondrial DNA (mtDNA) as potential biomarkers in cancer remains controversial.
Objective: To determine the concentration of cfDNA and plasma nDNA and mtDNA levels in breast cancer (BC) patients.
Material And Methods: This study included a total of 86 women (69 patients with BC and 17 women as a control group).
The ethics in research using data from the Instituto Nacional de Acceso a la Informacion.
Gac Med Mex
January 2024
Departamento Medicina Genómica y Toxicología Ambiental. Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México-Unidad Periférica Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán", Mexico City, Mexico.
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