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Do prokinetic agents provide symptom relief through acceleration of gastric emptying? An update and revision of the existing evidence.
United European Gastroenterol J
March 2023
Translational Research Center for Gastrointestinal Disorders, Leuven, Belgium.
Background: Gastroparesis and functional dyspepsia are disorders characterized by upper gastrointestinal symptoms and multifaceted etiologies. One of the main therapeutic approaches is accelerating gastric emptying (GE) by means of prokinetic agents. Their efficacy has been demonstrated, although the association between symptom improvement and acceleration of emptying is less clear.
View Article and Find Full Text PDFGlossitis in an older non-corgi dog: Diagnosis and long-term follow-up.
Can Vet J
August 2022
University of Wisconsin - Madison, School of Veterinary Medicine, Department of Medical Sciences, Madison, Wisconsin, USA (Krenzke, Cameron, Pritchard); Southeast Veterinary Neurology of Boynton Beach, Boynton Beach, Florida, USA (Webb); Comparative Neuromuscular Laboratory, University of California - San Diego, La Jolla, California, USA (Guo, Shelton).
A 9-year-old spayed female 18.8 kg mixed breed boxer dog was referred for evaluation of a 7-month history of difficulty swallowing and prehending food, regurgitation, hypersalivation, and an abnormal dorsiflexion of the tongue. Prior to referral, a barium study was performed, which revealed a mildly dilated esophagus.
View Article and Find Full Text PDFFunctional dyspepsia is one of the most common functional disorders of the gastrointestinal tract, which resulted from impaired motor skills, visceral hypersensitivity, increased mucosal permeability, disorders of the autonomic nervous system, etc. There is no specific therapy for this disease, which often leads to the irrational use of various groups of drugs. Drug therapy is recommended only during periods of symptoms.
View Article and Find Full Text PDF[Feasibility of the determination of plasma vardenafil level in rat by performance liquid chromatography-tandem mass spectrometry].
Zhonghua Xin Xue Guan Bing Za Zhi
June 2020
College of Clinical Medicine, Hebei University, Baoding 071000, China; Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
To develope and validate a reliable and sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for determination of vardenafil concentration in plasma of rat. Plasma samples of normal Sprague-Dawley rats were collected. A Phenomenex Synergi Polar-RP 80A column (2.
View Article and Find Full Text PDFAcupuncture for symptomatic gastroparesis.
Cochrane Database Syst Rev
December 2018
Department of Korean Medicine, Pusan National University Hospital, Gudeok-Ro, Seo-Gu, Busan, Korea, South, 49241.
Background: Gastroparesis, a state of delayed gastric emptying in the absence of mechanical obstruction of the stomach, has a substantial impact on people's daily function and quality of life when symptomatic. Current treatment options are based on limited evidence of benefits. Acupuncture is widely used to manage gastrointestinal disorders, although its role in people with symptomatic gastroparesis is unclear.
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