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Safety and efficacy of pre-exposure prophylaxis with tixagevimab/cilgavimab (Evusheld) in patients with glomerular diseases who received rituximab.
Clin Kidney J
September 2023
University Center of Excellence on Nephrologic, Rheumatologic and Rare Diseases (ERK-net, ERN-Reconnect and RITA-ERN Member) with Nephrology and Dialysis Unit and Center of Immuno-Rheumatology and Rare Diseases (CMID), Coordinating Center of the Interregional Network for Rare Diseases of Piedmont and Aosta Valley, San Giovanni Bosco Hub Hospital, Turin, Italy.
Article Synopsis
- * After administering the treatment to 22 patients, none developed symptomatic SARS-CoV-2 infections during the observation period, while 39.3% of the control group experienced symptomatic infections, highlighting the treatment's potential benefits.
- * Overall, the findings suggest that tixagevimab/cilgavimab is a safe option that may significantly reduce the risk of symptomatic COVID-19 infections for vaccinated individuals with GD on anti-CD20 therapy.
A case of elderly-onset Crescentic Henoch-Schönlein purpura nephritis with hypocomplementemia and positive MPO-ANCA.
J Korean Med Sci
August 2012
Division of Nephrology, Department of Internal Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea.
Henoch-Schönlein purpura (HSP) is common in childhood and often self-limiting. There have been limited studies on elderly-onset HSP nephritis (HSPN). A 76-yr-old man was transferred to our hospital with a 1-month history of oliguria, abdominal pain, edema and palpable purpura in the legs.
View Article and Find Full Text PDFAzathioprine hypersensitivity presenting as cardiogenic shock and Sweet's syndrome in a patient with microscopic polyangiitis.
Intern Med
January 2013
Department of General Medicine, Flinders Medical Centre, Australia.
Azathioprine hypersensitivity is a clinical syndrome which may manifest from isolated fever and rash to multi-organ failure. This rare condition is usually self-limiting following the discontinuation of azathioprine. Therefore, it is important to maintain a high index of clinical suspicion for hypersensitivity reactions with azathioprine therapy.
View Article and Find Full Text PDFDetection of anti-neutrophil antibodies in autoimmune neutropenia of infancy: a multicenter study.
Isr Med Assoc J
February 2010
Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Background: Autoimmune neutropenia of infancy is caused by neutrophil-specific autoantibodies. Primary AIN is characterized by neutrophil count < 500 ml and a benign self-limiting course. Detecting specific antibodies against the polymorphic human neutrophil antigen usually confirms the diagnosis.
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