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OptimCLM: Optimizing clinical language models for predicting patient outcomes via knowledge distillation, pruning and quantization.
Int J Med Inform
December 2024
Apurba NSU R&D Lab, Department of Electrical and Computer Engineering, North South University, Dhaka, Bangladesh.
Background: Clinical Language Models (CLMs) possess the potential to reform traditional healthcare systems by aiding in clinical decision making and optimal resource utilization. They can enhance patient outcomes and help healthcare management through predictive clinical tasks. However, their real-world deployment is limited due to high computational cost at inference, in terms of both time and space complexity.
View Article and Find Full Text PDFClinical Use of Eltrombopag and Avatrombopag in Pediatric ITP in China: A Real-World Multicenter Retrospective Cohort Study.
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Hemophilia Comprehensive Care Center, Hematology Department, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Recent Developments in Aptamer-Based Sensors for Diagnostics.
Sensors (Basel)
November 2024
School of Chemistry and Chemical Engineering, Northwestern Polytechnical University, Xi'an 710072, China.
Chronic and non-communicable diseases (NCDs) account for a large proportion of global disorders and mortality, posing significant burdens on healthcare systems. Early diagnosis and timely interference are critical for effective management and disease prevention. However, the traditional methods of diagnosis still suffer from high costs, time delays in processing, and infrastructure requirements that are usually unaffordable in resource-constrained settings.
View Article and Find Full Text PDFReal-Time Quantification of Molecular-Level Dynamic Behaviors Underpinning Shear Thinning in End-Linked Associative Polymer Networks.
J Am Chem Soc
December 2024
Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.
Shear thinning of associative polymers is tied to bond breakage under deformation and retraction of dangling chains, as predicted by transient network theories. However, an in-depth understanding of the molecular mechanisms is limited by our ability to measure the molecular states of the polymers during deformation. Herein, utilizing a custom-built rheo-fluorescence setup, bond dissociation in model end-linked associative polymers is quantified in real time with nonlinear shear deformation based on a fluorescence quench transition when phenanthroline ligands bind with Ni.
View Article and Find Full Text PDF[The USSR food crisis in XX century: the middle of 1950s - the first half of 1960s].
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N. A. Semashko National Research Institute of Public Health, 105064, Moscow, Russia,
The article is devoted to nutrition of population in the USSR during governing of N. S. Khrushchev in 1955-1964.
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