AI Article Synopsis
- The study compares the accuracy of two devices, BiliCheck™ and JM-103, for measuring total serum bilirubin (TSB) in 630 neonates.
- While both devices show good correlation with TSB, BiliCheck™ tends to underestimate bilirubin levels more than JM-103.
- JM-103 is cheaper and more efficient to use, suggesting it may be the preferred option, but further research is needed to assess its effectiveness for widespread screening of severe hyperbilirubinemia.
Article Abstract
Objectives: To compare the accuracy of BiliCheck™ (Respironics, Marietta, GA) and Konica-Minolta Air Shield JM-103 (Drager Medical Inc, Telford, PA) to evaluate total serum bilirubin (TSB).
Methods: Prospective blinded study comparing two diagnostic devices in 630 neonates requiring TSB measurement.
Results: Linear regression analysis showed a good correlation between BiliCheck™ and TSB (r=0.8212) as well as between JM-103 and TSB (r=0.8686). BiliCheck shows a tendency to underestimate TSB. The mean difference in TSB-TcB was -1.4 mg/dL for BC (-4.7/+1.8 mg/dL) and 0.3 mg/dL for JM-103 (-2.6/+3.2mg/dL). ROC analysis for TSB≥ 12 mg/dL showed area under the curve for BiliCheck™ significantly lower than those for JM-103 (p<0.0001). JM-103 resulted less time expensive than BiliCheck.
Conclusions: In spite of similar diagnostic accuracy JM-103 could be preferred for some practical advantages, but its suitability in performing universal screening for severe hyperbilirubinemia deserves further investigations.
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| http://dx.doi.org/10.1016/j.clinbiochem.2012.03.014 | DOI Listing |
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