Pluripotent stem cell-based cancer therapy: promise and challenges.

Sci Transl Med

Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

Published: March 2012

AI Article Synopsis

  • Induced pluripotent stem cell (iPSC) technology shows promise for treating various diseases, generating excitement in the medical field.
  • Despite the enthusiasm, there's limited evidence supporting their effectiveness in real-world clinical scenarios.
  • The text outlines potential applications for iPSCs in cancer treatment and identifies existing challenges that hinder their broader use in healthcare.

Article Abstract

The development of induced pluripotent stem cell (iPSC) technology has generated enthusiasm about the therapeutic potential of these cells for treating a variety of diseases. However, the evidence that they actually will be clinically useful is limited. Here, we discuss the potential therapeutic applications of iPSCs for treating cancer and other diseases and highlight the current barriers restricting their use.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397797PMC
http://dx.doi.org/10.1126/scitranslmed.3003920DOI Listing

Publication Analysis

Top Keywords

pluripotent stem
8
stem cell-based
4
cell-based cancer
4
cancer therapy
4
therapy promise
4
promise challenges
4
challenges development
4
development induced
4
induced pluripotent
4
stem cell
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!