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Progressive supranuclear palsy: an updated approach on diagnosis, treatment, risk factors and outlook in Mexico.
Gac Med Mex
January 2025
Laboratorio de Reprogramación Celular y Enfermedades Crónico-Degenerativas, Department of Physiology, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Progressive supranuclear palsy (PSP) is a rare, atypical parkinsonism, characterized by the presence of intracerebral tau protein aggregates and determined by a wide spectrum of clinical features. The definitive diagnosis is postmortem and is identified through the presence of neuronal death, gliosis, and aggregates of the tau protein presented in the form of neurofibrillary tangles (MNF) with a globose appearance in regions such as the subthalamic nucleus, the substantia nigra, and the globus pallidus The findings in ancillary imaging studies, as well as fluids biomarkers, are not sufficient to support diagnosis of PSP but are used to rule out similar pathologies because there are still no specific or validated biomarkers for this disease. The current treatment of PSP is focused on reducing symptoms, although emerging therapies seek to counteract its pathophysiological mechanisms.
View Article and Find Full Text PDFResponses of biological characteristics and detoxification enzymes in the fall armyworm to methoxyfenozide stress.
J Econ Entomol
January 2025
Hubei Engineering Technology Center of Forewarning and Management of Agricultural and Forestry Pests, Yangtze University, Jingzhou 434000, PR China.
Methoxyfenozide is an insecticide with a unique mode of action on the insect ecdysone receptor and has been registered for the control of insect pests all over the world. In the present work, Spodoptera frugiperda was exposed to sublethal and lethal concentrations of methoxyfenozide to determine its impact on specific biological traits, metabolic enzyme activity, and the expression of detoxification enzymes. The result showed that 72-h posttreatment with LC50 and LC70 of methoxyfenozide significantly reduced the fecundity (eggs/female) of the F0 generation compared to those of the control group.
View Article and Find Full Text PDFEffect of ultrasound combined with edible coating based on guar gum on the physicochemical quality and texture of fried zucchini slices.
J Food Sci
January 2025
Department of Food Science and Technology, Faculty of Food Industry, Bu-Ali Sina University, Hamedan, Iran.
Edible coating (EC) can reduce excessive oil absorption in deep-fat fried food products. Ultrasound is an efficient pretreatment to preserve the quality characteristics of fried samples. The impact of guar gum based EC and sonication on the quality parameters of fried zucchini slices was investigated.
View Article and Find Full Text PDFThis study aimed to investigate the impact of dietary soybean oil and probiotics on goat meat quality, total conjugated linoleic acids (TCLA) concentration, and nutritional quality indicators of goats. Thirty-six male crossbred goats (Anglo-Nubian♂× Thai native♀), weighing 18.3 ± 2.
View Article and Find Full Text PDFSimultaneous extraction and purification of polysaccharides and proteins from Pleurotus ostreatus using an aqueous two-phase system.
J Food Sci
January 2025
College of Food Science and Engineering, Nanjing University of Finance and Economics/Collaborative Innovation Center for Modern Grain Circulation and Safety, Nanjing, China.
Pleurotus ostreatus is a nutrient-dense edible fungus renowned for its delicate texture, appealing flavor, and numerous potential health benefits. Simultaneous extraction within the framework of food resource processing facilitates the concurrent isolation and analysis of multiple target compounds. In this study, an ethanol/salt aqueous two-phase system (ATPS) was employed to extract polysaccharides (PS) and proteins from P.
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