Genetic polymorphism of serum complement components in the chimpanzee.

Immunogenetics

Department of Medicine, Children's Hospital Medical Center, Boston, Massachusetts 02115, USA.

Published: May 2012

Significant polymorphism of serum complement components Bf, C2, C3, C6, and C8 in the chimpanzee has been demonstrated. The data are consistent with the hypothesis that C2 and Bf are closely linked to ChLA and argue against close linkage of ChLA to C3 or to C8, as in man. In addition, a blank allele for C6 and C6 deficiency was detected in several chimps.

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http://dx.doi.org/10.1007/BF01572581DOI Listing

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