Information on important source areas for dissolved solids in streams of the southwestern United States, the relative share of deliveries of dissolved solids to streams from natural and human sources, and the potential for salt accumulation in soil or groundwater was developed using a SPAtially Referenced Regressions On Watershed attributes model. Predicted area-normalized reach-catchment delivery rates of dissolved solids to streams ranged from <10 (kg/year)/km(2) for catchments with little or no natural or human-related solute sources in them to 563,000 (kg/year)/km(2) for catchments that were almost entirely cultivated land. For the region as a whole, geologic units contributed 44% of the dissolved-solids deliveries to streams and the remaining 56% of the deliveries came from the release of solutes through irrigation of cultivated and pasture lands, which comprise only 2.5% of the land area. Dissolved-solids accumulation is manifested as precipitated salts in the soil or underlying sediments, and (or) dissolved salts in soil-pore or sediment-pore water, or groundwater, and therefore represents a potential for aquifer contamination. Accumulation rates were <10,000 (kg/year)/km(2) for many hydrologic accounting units (large river basins), but were more than 40,000 (kg/year)/km(2) for the Middle Gila, Lower Gila-Agua Fria, Lower Gila, Lower Bear, Great Salt Lake accounting units, and 247,000 (kg/year)/km(2) for the Salton Sea accounting unit.
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http://dx.doi.org/10.1111/j.1752-1688.2011.00579.x | DOI Listing |
J Pharm Sci
January 2025
Department of Synthetic Molecule Pharmaceutical Sciences, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA. Electronic address:
It is desirable but remains challenging to develop high drug load amorphous solid dispersions (ASDs) without compromising their quality attributes and bio-performance. In this work, we investigated the impacts of formulation variables, such as drug loading (DL) and polymer type, on dissolution behavior, diffusive flux, and in vitro drug absorption of ASDs of a high T compound, GDC-6893. ASDs with two polymers (HPMCAS and PVPVA) and various DLs (20 - 80%) were produced by spray drying and their drug-polymer miscibility was evaluated using solid-state nuclear magnetic resonance (ssNMR).
View Article and Find Full Text PDFWaste Manag
January 2025
Earth Sciences Department, University of Turin 10125 Turin, Italy.
This study investigates steam washing (SW) as an innovative pretreatment for municipal solid waste incineration fly ash (MSWI-FA) dechlorination, useful for a more effective stabilization in cementitious matrix. By using a detailed analytical approach (XRPD, XRF, ICP-MS, IRMS, SEM) and geochemical modeling, great focus is dedicated on pollutant leaching reduction and changes in ash physicochemical characteristics as a function of exposure time. The research demonstrates that SW removes up to 70 % cadmium, 17 % zinc, and 10 % lead, primarily by dissolving the soluble and carbonate/hydroxide fractions and promoting the reprecipitation and adsorption of heavy metals into more stable compounds.
View Article and Find Full Text PDFAnal Chem
January 2025
Institute of Analytical Chemistry, Chemo- and Biosensors, University of Regensburg, Universitaetsstr. 31, Regensburg 93053, Germany.
To ensure high quality of food and water, the identification of traces of pathogens is mandatory. Rapid nucleic acid-based tests shorten traditional detection times while maintaining low detection limits. Challenging is the loss of nucleic acids during necessary purification processes, since elution off solid surfaces is not efficient.
View Article and Find Full Text PDFFood Chem X
January 2025
Research Center for Applied Zoology, National Research and Innovation Agency Republic of Indonesia, P.O. Box 16911, Bogor, Indonesia.
Indonesia, one of the largest tropical forests, offers a diverse range of nectar sources that contribute to the unique characteristics of forest honey. This study aims to investigate physicochemical and antioxidant properties of forest honey from three distinct regions of Indonesia. Key physicochemical parameters include moisture, color, electrical conductivity (EC), total dissolved solids (TDS), total suspended solids (TSS), density, diastase number (DN), hydroxymethylfurfural (HMF), pH, total acidity, ash content, protein content, and reducing sugars.
View Article and Find Full Text PDFThe dissolution/diffusion process of solid in a liquid is a kind of widespread physical phenomenon. Parameters involved in this process include the dissolution rate (), dissolution rate constant (), and diffusion coefficient (), whose accurate measurement is particularly important in fields such as biopharmaceuticals, materials science, agriculture, etc. However, the commonly used measurement methods at present cannot obtain these parameters simultaneously.
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