AI Article Synopsis
- Palladium-catalyzed reactions successfully used inexpensive gem-dichloroalkenes as electrophiles for alkynylating heteroarenes.
- This method enables a modular and efficient synthesis of various heteroaryl alkynes.
- The approach offers plenty of flexibility in designing differently substituted alkynes.
Article Abstract
Palladium-catalyzed direct alkynylations of heteroarenes were accomplished with inexpensive gem-dichloroalkenes as user-friendly electrophiles, which set the stage for a modular, step-economical synthesis of diversely decorated heteroaryl alkynes with ample scope.
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| http://dx.doi.org/10.1021/ol300514d | DOI Listing |
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