Threefold exposure to moderate hypobaric hypoxia decreases the expression of Cu,Zn-superoxide dismutase in some regions of rat hippocampus.

Bull Exp Biol Med

Laboratory for Regulation of Brain Neuron Functions, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg, Russia.

Published: July 2011

The effect of moderate hypobaric hypoxia on the expression of a peptide antioxidant Cu,Zn-superoxide dismutase in rat hippocampal neurons was evaluated in an immunocytochemical study. The expression of Cu,Zn-superoxide dismutase decreased significantly in the dorsal hippocampus (CA1 and CA2) and tended to decrease in ventral regions (CA3 and dentate gyrus) by the 24th hour after 3-fold exposure to hypoxia.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10517-011-1314-zDOI Listing

Publication Analysis

Top Keywords

cuzn-superoxide dismutase
12
moderate hypobaric
8
hypobaric hypoxia
8
expression cuzn-superoxide
8
threefold exposure
4
exposure moderate
4
hypoxia decreases
4
decreases expression
4
dismutase regions
4
regions rat
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!